4.7 Article

Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections

Journal

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Volume 99, Issue -, Pages 19-22

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2020.07.034

Keywords

COVID-19; SARS-CoV-2; Olfactory/taste disorders (OTDs); Real-time polymerase chain reaction (qPCR); Cycle threshold (Ct) values

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This study investigated, using cycle threshold (Ct) qPCR values, the association between symptoms and viral clearance in 57 patients with asymptomatic/mild SARS-CoV-2 infection. Patients with olfactory/taste disorders (OTDs) exhibited lower qPCR Ct values and longer time to negative qPCR than those without OTDs, suggesting an association between OTDs and high viral burden. (c) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

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