Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 154, Issue -, Pages 732-738Publisher
ELSEVIER
DOI: 10.1016/j.ijbiomac.2020.03.139
Keywords
Supramolecular film; Antibacterial activity; Analysis of action mechanism; Cytocompatibility
Funding
- National Natural Science Foundation of China [21671055, 21601048]
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This paper reported a facile strategy to fabricate ionically crosslinked supramolecular film, in which an in situ formed chitosan ionic film was produced by post-crosslinking the chitosan chains using negatively charged anion polyoxometalate. The incorporation of polyoxometalate into the chitosan ionic system accelerated the crosslinked degree, as evidenced by an increase in surface wrinkle via scanning electron microscopy. Interestingly, the resultant supramolecular film realized the combination of prominent antimicrobial effect and excellent biocompatibility, which was considered to have enormous application potential range from biomedical to environmental science. (C) 2020 Elsevier B.V. All rights reserved.
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