Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 154, Issue -, Pages 1074-1081Publisher
ELSEVIER
DOI: 10.1016/j.ijbiomac.2020.02.324
Keywords
Auricularia; Polysaccharides; Digestion; Anti-inflammatory; Function
Funding
- Northeast Agricultural University [18XG28]
- National Key Research and Development Program of China [2018YFD0400500, 2018YFD0400503]
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Four Auricularia polysaccharides (A.cornea (ACP), A.auricula (AAP), A.polytricha (APP) and M.fungus (MFP)) were researched to evaluate the effect of Auricularia species on digestion, anti-inflammatory and function of polysaccharides. The results showed that the molecular weights of ACP and MFP were significantly reduced in gastric juice from 30 min to 150 min (p < 0.05), the polysaccharides were degraded into small molecules and their structures were changed after digestion. The inhibition rate of alpha-amylase and alpha-glucosidase of APP were 71.21% and 82.01%, respectively, APP had a better hypolipidemic activity and the inhibitory activity was 89.5%. AAP, APP, and MFP could significantly promoted cell proliferation at 400 mu g/mL. Four polysaccharides could inhibit inflammatory factors, so all polysaccharides have the good anti-inflammatory activity. The minimal inhibitory concentration (MIC) of APP against E. coli and S. typhi were 1.25% and 1.0%, respectively. There were significant differences in the digestion, anti-inflammatory and function of Auricularia polysaccharides among different species (p < 0.05). (C) 2020 Elsevier B.V. All rights reserved.
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