Journal
CLINICAL AND EXPERIMENTAL MEDICINE
Volume 17, Issue 3, Pages 411-414Publisher
SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s10238-016-0437-y
Keywords
Systemic sclerosis; Undifferentiated connective tissue disease
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The aim of the study was to evaluate CXCL4 levels in undifferentiated connective tissue disease at risk for SSc (UCTD-SSc-risk) and confirm its increase and investigate its prognostic value. Serum CXCL4 levels were measured in 45 patients and 24 controls. CXCL4 was significantly higher in UCTD-SSc-risk patients than in controls. It resulted higher in patients with a shorter disease duration and in those lacking capillaroscopic alterations. We confirm that CXCL4 levels are increased in UCTD-risk-SSc patients. Further studies are needed to investigate the role of CXCL4 assessment in UCTD-risk-SSc.
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