Journal
INFECTION
Volume 48, Issue 4, Pages 631-634Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s15010-020-01461-0
Keywords
COVID-19; SARS-CoV-2; Immunoglobulin; IgG; IgA; Health-care worker; ELISA; Seroprevalence; Diagnostics; Health-care professionals
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There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal likelihood of having had a SARS-CoV-2 infection with a mean of 21% [median 15%, interquartile range (IQR) 5-30%]. In contrast, anti-SARS-CoV-2 IgG prevalence was about 1-2% at baseline. Regular anti-SARS-CoV-2 IgG testing of health-care professionals may aid in directing resources for protective measures and care of COVID-19 patients in the long run.
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