Related references
Note: Only part of the references are listed.Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons
Hong Chen et al.
CELL STEM CELL (2014)
Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1
Evangelos Kiskinis et al.
CELL STEM CELL (2014)
Missense Mutations in Plakophilin-2 Cause Sodium Current Deficit and Associate With a Brugada Syndrome Phenotype
Marina Cerrone et al.
CIRCULATION (2014)
Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons
Emily Cunningham Williams et al.
HUMAN MOLECULAR GENETICS (2014)
Human-induced pluripotent stem cells: potential for neurodegenerative diseases
Christopher A. Ross et al.
HUMAN MOLECULAR GENETICS (2014)
A guide to genome engineering with programmable nucleases
Hyongbum Kim et al.
NATURE REVIEWS GENETICS (2014)
Pluripotent stem cells in regenerative medicine: challenges and recent progress
Viviane Tabar et al.
NATURE REVIEWS GENETICS (2014)
In Vivo Roles of a Patient-Derived Induced Pluripotent Stem Cell Line (HD72-iPSC) in the YAC128 Model of Huntington’s Disease
Iksoo Jeon et al.
International Journal of Stem Cells (2014)
Disease modeling and cell based therapy with iPSC: future therapeutic option with fast and safe application
Changsung Kim
BLOOD RESEARCH (2014)
Current status of drug screening and disease modelling in human pluripotent stem cells
Divya Rajamohan et al.
BIOESSAYS (2013)
Substrate stiffness affects sarcomere and costamere structure and electrophysiological function of isolated adult cardiomyocytes
Peter A. Galie et al.
CARDIOVASCULAR PATHOLOGY (2013)
Isogenic Human iPSC Parkinson's Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription
Scott D. Ryan et al.
CELL (2013)
Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
Justine D. Miller et al.
CELL STEM CELL (2013)
Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
Peter Reinhardt et al.
CELL STEM CELL (2013)
A Small Molecule Screen in Stem-Cell-Derived Motor Neurons Identifies a Kinase Inhibitor as a Candidate Therapeutic for ALS
Yin M. Yang et al.
CELL STEM CELL (2013)
Modeling Alzheimer's Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
Takayuki Kondo et al.
CELL STEM CELL (2013)
Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells
Feng Lan et al.
CELL STEM CELL (2013)
Drug Screening Using a Library of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveals Disease-Specific Patterns of Cardiotoxicity
Ping Liang et al.
CIRCULATION (2013)
Induced Pluripotent Stem Cell-Derived Cardiomyocytes Boutique Science or Valuable Arrhythmia Model?
Bjoern C. Knollmann
CIRCULATION RESEARCH (2013)
Genome editing of human pluripotent stem cells to generate human cellular disease models
Kiran Musunuru
DISEASE MODELS & MECHANISMS (2013)
Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
Su Mi Choi et al.
HEPATOLOGY (2013)
Investigation of Rett Syndrome Using Pluripotent Stem Cells
Rana Dajani et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2013)
Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration
Xing Guo et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics
Cecile Terrenoire et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
Modeling Huntington's disease with induced pluripotent stem cells
Julia A. Kaye et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2013)
Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs
Changsung Kim et al.
NATURE (2013)
CRISPR RNA-guided activation of endogenous human genes
Morgan L. Maeder et al.
NATURE METHODS (2013)
Remodeling Neurodegeneration: Somatic Cell Reprogramming-Based Models of Adult Neurological Disorders
Liang Qiang et al.
NEURON (2013)
Induction of human cardiomyocyte-like cells from fibroblasts by defined factors
Rie Wada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Genomic responses in mouse models poorly mimic human inflammatory diseases
Junhee Seok et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
High Throughput Screening for Inhibitors of REST in Neural Derivatives of Human Embryonic Stem Cells Reveals a Chemical Compound that Promotes Expression of Neuronal Genes
Jeremie Charbord et al.
STEM CELLS (2013)
Effect of substrate stiffness on early human embryonic stem cell differentiation
Nikolai Eroshenko et al.
JOURNAL OF BIOLOGICAL ENGINEERING (2013)
Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State
Ji-Dong Fu et al.
STEM CELL REPORTS (2013)
Huntington's disease: Dancing in a dish
Kejing Zhang et al.
CELL RESEARCH (2012)
Discovery of Inhibitors of Microglial Neurotoxicity Acting Through Multiple Mechanisms Using a Stem-Cell-Based Phenotypic Assay
Susanne Hoeing et al.
CELL STEM CELL (2012)
Pathophysiology of the cardiac late Na current and its potential as a drug target
Jonathan D. Moreno et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
Inhibition of Apoptosis Blocks Human Motor Neuron Cell Death in a Stem Cell Model of Spinal Muscular Atrophy
Dhruv Sareen et al.
PLOS ONE (2012)
Cardiomyocytes derived from human pluripotent stem cells for drug screening
Naama Zeevi-Levin et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling
Xiaojun Lian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient-Derived Induced Pluripotent Stem Cells
Iksoo Jeon et al.
STEM CELLS (2012)
Cardiac muscle regeneration: lessons from development
Mark Mercola et al.
GENES & DEVELOPMENT (2011)
Modeling familial Alzheimer's disease with induced pluripotent stem cells
Takuya Yagi et al.
HUMAN MOLECULAR GENETICS (2011)
Modelling schizophrenia using human induced pluripotent stem cells
Kristen J. Brennand et al.
NATURE (2011)
Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
Masayuki Yazawa et al.
NATURE (2011)
Modelling the long QT syndrome with induced pluripotent stem cells
Ilanit Itzhaki et al.
NATURE (2011)
A screen for regulators of survival of motor neuron protein levels
Nina R. Makhortova et al.
NATURE CHEMICAL BIOLOGY (2011)
Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model
Gene Ananiev et al.
PLOS ONE (2011)
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors
Hiroshi Ban et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Induced Pluripotent Stem Cells Can Be Used to Model the Genomic Imprinting Disorder Prader-Willi Syndrome
Jiayin Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation
Gary D. Lopaschuk et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2010)
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
Xonia Carvajal-Vergara et al.
NATURE (2010)
Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome.
Alessandra Moretti et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
An Autophagy-Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis
Tunda Hidvegi et al.
SCIENCE (2010)
Non-Cardiomyocytes Influence the Electrophysiological Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes During Differentiation
Changsung Kim et al.
STEM CELLS AND DEVELOPMENT (2010)
A potential link between peroxisome proliferator-activated receptor signalling and the pathogenesis of arrhythmogenic right ventricular cardiomyopathy
Fatima Djouadi et al.
CARDIOVASCULAR RESEARCH (2009)
Cardiac Ion Channels
Augustus O. Grant
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2009)
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Stuart M. Chambers et al.
NATURE BIOTECHNOLOGY (2009)
Lessons from 60 years of pharmaceutical innovation
Bernard Munos
NATURE REVIEWS DRUG DISCOVERY (2009)
Disease-specific induced pluripotent stem cells
In-Hyun Park et al.
CELL (2008)
Therapeutic Strategies for Long-QT Syndrome Does the Molecular Substrate Matter?
Yanfei Ruan et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2008)
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
Adam J. Engler et al.
JOURNAL OF CELL SCIENCE (2008)
Human cardiovascular progenitor cells develop from a KDR plus embryonic-stem-cell-derived population
Lei Yang et al.
NATURE (2008)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
Regulation of cardiomyocyte differentiation of embryonic stem cells by extracellular signalling
A. A. Filipczyk et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
A non-sequence-specific requirement for SMN protein activity: the role of aminoglycosides in inducing elevated SMN protein levels
EC Wolstencroft et al.
HUMAN MOLECULAR GENETICS (2005)
The impact of drug-induced qt interval prolongation on drug discovery and development
B Fermini et al.
NATURE REVIEWS DRUG DISCOVERY (2003)
In vitro differentiation of transplantable neural precursors from human embryonic stem cells
SC Zhang et al.
NATURE BIOTECHNOLOGY (2001)
Neural progenitors from human embryonic stem cells
BE Reubinoff et al.
NATURE BIOTECHNOLOGY (2001)
Share Paper
