Journal
CIRCULATION RESEARCH
Volume 119, Issue 12, Pages 1280-1282Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/CIRCRESAHA.116.309942
Keywords
biomarkers; cardiovascular system; exosome; microRNA; systems biology
Funding
- NHLBI NIH HHS [R56 HL124380] Funding Source: Medline
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Exosomes, once thought to be biomarkers of a diseased state, are now thought to be biologically active and some of the paracrine effects of stem cell therapy. Although there is much excitement around their actions, there is also a growing need to better understand the role of cell source, exosome content, and exosome targeting in a quantitative manner. Better understanding of these variables and others, in a reproducible and comprehensive approach, could better inform future therapy.
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