Journal
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
Volume 22, Issue 7, Pages 898-911Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389201021666200807111359
Keywords
COVID 19; Traditional medicine; Ayurveda; Phytochemical; Quercetin
Funding
- Amrita VishwaVidyapeetham Research grant
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SARS-CoV 2, a novel Coronavirus strain, has no specific treatment currently available. Indian Traditional Medicine, Ayurveda, offers potential antiviral remedies through seven traditional plants. Research on dietary polyphenol Quercetin as a potential drug candidate against the virus is also highlighted.
SARS-CoV 2 is a novel virus strain of Coronavirus, reported in China in late December 2019. Its highly contagious nature in humans has prompted WHO to designate the ongoing pandemic as a Public Health Emergency of International Concern. At this moment, there is no specific treatment and the therapeutic strategies to deal with the infection are only supportive, with prevention aimed at reducing community transmission. A permanent solution for the pandemic, which has brought the world economy to the edge of collapse, is the need of the hour. This situation has brought intense research in traditional systems of medicine. Indian Traditional System, Ayurveda, has a clear concept of the cause and treatment of pandemics. Through this review, information on the potential antiviral traditional medicines along with their immunomodulatory pathways are discussed. We have covered the seven most important Indian traditional plants with antiviral properties: Withania somnifera (L.) Dunal (family: Solanaceae), Tinospora cordifolia (Thunb.) Miers (family: Menispermaceae), Phyllanthus emblica L. (family: Euphorbiaceae), Asparagus racemosus L. (family: Liliaceae), Glycyrrhiza glabra L. (family: Fabaceae), Ocimum sanctum L.(family: Lamiaceae) and Azadirachta indica A. Juss (family: Meliaceae) in this review. An attempt is also made to bring into limelight the importance of dietary polyphenol, Quercetin, which is a potential drug candidate in the making against the SARS-CoV2 virus.
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