4.5 Review

Recent progress in the development of organometallics for the treatment of cancer

Journal

CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 56, Issue -, Pages 28-34

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2019.11.001

Keywords

Bioorganometallic chemistry; Bioinorganic chemistry; Metallodrugs; Chemotherapy

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From their early successes in medicine, organometallic com- pounds continue to attract interest as potential chemotherapeutics to treat a range of diseases. Here, we show from recent literature selected largely from the last two years that organometallics offer unique opportunities in medicine and, increasingly, a mechanistic-based approach is applied to their development, which has not always been the case.

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