Journal
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
Volume 61, Issue 13, Pages 2262-2276Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2020.1775546
Keywords
COVID-19; inflammation; obesity; SARS-CoV-2; viral
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Funding
- FAPESP [19/02679-7]
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [19/02679-7] Funding Source: FAPESP
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This review summarizes the relationship between obesity and the severity and prognosis of COVID-19, including changes in immune response, nutritional factors, physiological factors, and the gut-lung axis.
The current coronavirus disease-2019 (COVID-19) pandemic presents a huge challenge for health-care systems worldwide. Many different risk factors are associated with disease severity, such as older age, diabetes, hypertension, and most recently obesity. The incidence of obesity has been on the rise for the past 25 years, reaching over 2 billion people throughout the world, and obesity itself could be considered a pandemic. In this review, we summarize aspects involved with obesity, such as changes in the immune response, nutritional factors, physiological factors, and the gut-lung axis, that impact the viral response and the COVID-19 prognosis.
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