Journal
CLINICAL INFECTIOUS DISEASES
Volume 73, Issue 9, Pages E3102-E3105Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa1165
Keywords
SARS-CoV-2; neurological manifestations; COVID-19; intrathecal synthesis; blood-brain barrier
Categories
Ask authors/readers for more resources
This study analyzed the cerebrospinal fluid features of 31 COVID-19 patients with neurological complications and found no SARS-CoV-2 RNA or intrathecal IgG synthesis, but observed signs of blood-brain barrier disruption. These results may help improve understanding of SARS-CoV-2 related neuropathogenesis.
This study analyzed the cerebrospinal fluid features of 31 coronavirus disease 2019 (COVID-19) patients with neurological complications. We observed neither severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in the cerebrospinal fluid, nor intrathecal immunoglobulin G (IgG) synthesis but did observe signs of blood-brain barrier disruption. These results might serve as a basis for a better understanding of SARS-CoV-2 related neuropathogenesis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available