Journal
CLINICAL INFECTIOUS DISEASES
Volume 72, Issue 6, Pages 1064-1066Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa848
Keywords
COV1D-19; SARS-CoV-2; nasopharyngeal swab; saliva
Categories
Funding
- Canadian Institutes of Health Research [COVID-19, 440359]
- Vanier Canada Graduate Scholarship
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A study of 91 inpatients with COVID-19 in Toronto, Canada, found that nasopharyngeal swabs had a sensitivity of 89% compared to saliva's 72% sensitivity when tested with real-time RT-PCR. The difference in sensitivity was more pronounced for sample pairs collected later in the course of the illness.
We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/ saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness.
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