Journal
CLINICAL INFECTIOUS DISEASES
Volume 74, Issue 1, Pages 127-132Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa964
Keywords
COVID-19; personalized therapy; pneumonia; patterns
Categories
Funding
- AGAUR of the Catalan Health Agency [2017SGR1432]
- EIT Health
- European Institute of Innovation and Technology (EIT), a body of the European Union from the European Union's Horizon 2020 Research and Innovation Program
- European Regional Development Fund (EDRD)
- Ministerio de Sanidad y Consumo, Instituto de Salud Carlos III [CM18/00132, FI19/00133, PI18/01061, FIS PI18/01061]
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Hospitalized patients with COVID-19 experiencing respiratory symptoms have different complications, which can be identified by analytical patterns. Personalized treatment decisions can decrease early mortality, while increasing age and therapeutic effort limitation are associated with higher mortality.
Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR] .144; 95% confidence interval [CI] .03-.686; P=.015). Increasing age (OR 1.06; P=.038) and therapeutic effort limitation (OR 9.684; P<.001) were associated with higher mortality.
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