Related references
Note: Only part of the references are listed.Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts
Le Bai et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)
Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities
Nikolaos G. Frangogiannis
MOLECULAR ASPECTS OF MEDICINE (2019)
Heart Disease and Stroke Statistics-2019 Update A Report From the American Heart Association
Emelia J. Benjamin et al.
CIRCULATION (2019)
Reactive Oxygen Species Drive Epigenetic Changes in Radiation-Induced Fibrosis
Shashank Shrishrimal et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Mitochondrial Biogenesis and Mitochondrial Reactive Oxygen Species (ROS): A Complex Relationship Regulated by the cAMP/PKA Signaling Pathway
Cyrielle Bouchez et al.
CELLS (2019)
Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts
Robert B. Hamanaka et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)
Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis
Huachun Cui et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)
TRPA1 Promotes Cardiac Myofibroblast Transdifferentiation after Myocardial Infarction Injury via the Calcineurin-NFAT-DYRK1A Signaling Pathway
Shuang Li et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis
Brintha Selvarajah et al.
SCIENCE SIGNALING (2019)
Caspases in Cell Death, Inflammation, and Disease
Nina Van Opdenbosch et al.
IMMUNITY (2019)
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis
Xuezhou Hou et al.
CELL REPORTS (2019)
Histone acetyltransferase inhibitors: An overview in synthesis, structure-activity relationship and molecular mechanism
Mengyuan Huang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Targeting cardiac fibrosis with engineered T cells
Haig Aghajanian et al.
NATURE (2019)
Metabolic regulation of gene expression by histone lactylation
Di Zhang et al.
NATURE (2019)
Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation
Alyssa A. Lombardi et al.
NATURE COMMUNICATIONS (2019)
Angiotensin II confers resistance to apoptosis in cardiac myofibroblasts through the AT1/ERK1/2/RSK1 pathway
Wenfeng Cai et al.
IUBMB LIFE (2019)
Fibroblasts in the Infarcted, Remodeling, and Failing Heart
Claudio Humeres et al.
JACC-BASIC TO TRANSLATIONAL SCIENCE (2019)
Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis
Eva Schruf et al.
RESPIRATORY RESEARCH (2019)
TGF-β1 modifies histone acetylation and acetyl-coenzyme A metabolism in renal myofibroblasts
Edward R. Smith et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2019)
Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation
Karen Bernard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Targeting Hypoxia-Inducible Factor-1 alpha/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis
Justin Goodwin et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2018)
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation
Jing Ge et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2018)
Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis
Robert B. Hamanaka et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2018)
BCL2 Regulates Differentiation of Intestinal Fibroblasts
Bruce Weder et al.
INFLAMMATORY BOWEL DISEASES (2018)
Dynamics of fibroblast activation in the infarcted heart
Alexandra Le Bras
NATURE REVIEWS CARDIOLOGY (2018)
FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts
Markaisa Black et al.
CELL REPORTS (2018)
Cadherin-11 as a regulator of valve myofibroblast mechanobiology
Meghan A. Bowler et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
Xing Fu et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Epigenetics in Cardiac Fibrosis Emphasis on Inflammation and Fibroblast Activation
Marina B. Felisbino et al.
JACC-BASIC TO TRANSLATIONAL SCIENCE (2018)
RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase
Mitsuru Imamura et al.
JCI INSIGHT (2018)
A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis
Rahul Rai et al.
EPIGENETICS (2017)
Cardiac macrophages adopt profibrotic/M2 phenotype in infarcted hearts: Role of urokinase plasminogen activator
Signe Carlson et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2017)
Redefining the identity of cardiac fibroblasts
Michelle D. Tallquist et al.
NATURE REVIEWS CARDIOLOGY (2017)
Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy
Tania Zaglia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis
David Lagares et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis
Franco Conforti et al.
ONCOTARGET (2017)
ATP-citrate lyase is essential for high glucose-induced histone hyperacetylation and fibrogenic gene upregulation in mesangial cells
Dilip K. Deb et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis
Hao Ding et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes
Andrew A. Gibb et al.
BIOCHEMICAL JOURNAL (2017)
Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis
Jeffery D. Molkentin et al.
CIRCULATION (2017)
Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy
Yusuke Kurita et al.
RESPIRATORY RESEARCH (2017)
Tensin 1 Is Essential for Myofibroblast Differentiation and Extracellular Matrix Formation
Ksenija Bernau et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2017)
Revisiting Cardiac Cellular Composition
Alexander R. Pinto et al.
CIRCULATION RESEARCH (2016)
Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin
Rance Nault et al.
TOXICOLOGICAL SCIENCES (2016)
Myofibroblast persistence with real-time changes in boundary stiffness
Mehmet H. Kural et al.
ACTA BIOMATERIALIA (2016)
Extracellular matrix structure
Achilleas D. Theocharis et al.
ADVANCED DRUG DELIVERY REVIEWS (2016)
Enjoy the Trip: Calcium in Mitochondria Back and Forth
Diego De Stefani et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)
Deregulation of energy metabolism promotes antifibrotic effects in human hepatic stellate cells and prevents liver fibrosis in a mouse model
Swathi Karthikeyan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation
Cyril Corbet et al.
CELL METABOLISM (2016)
Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice
Harmandeep Kaur et al.
CIRCULATION RESEARCH (2016)
Inside HDACs with more selective HDAC inhibitors
Joelle Roche et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction
B. A. Piras et al.
GENE THERAPY (2016)
Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production
Recep Nigdelioglu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis
Kenji Kobayashi et al.
JOURNAL OF IMMUNOLOGY (2016)
Epigenetic regulation of cardiac fibrosis
Matthew S. Stratton et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Molecular networks underlying myofibroblast fate and fibrosis
April Stempien-Otero et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems
Jason Pellman et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities
Ilaria Russo et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Genetic lineage tracing defines myofibroblast origin and function in the injured heart
Onur Kanisicak et al.
NATURE COMMUNICATIONS (2016)
Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation
Eoin McDonnell et al.
CELL REPORTS (2016)
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
Steven Zhao et al.
CELL REPORTS (2016)
Pharmacologic inhibition of lactate production prevents myofibroblast differentiation
Robert Matthew Kottmann et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis
Na Xie et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
Constitutive Activation of Transforming Growth Factor Beta Receptor 1 in the Mouse Uterus Impairs Uterine Morphology and Function
Yang Gao et al.
BIOLOGY OF REPRODUCTION (2015)
Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells
Arieh Moussaieff et al.
CELL METABOLISM (2015)
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
Federico Pietrocola et al.
CELL METABOLISM (2015)
Eukaryotic initiation factor 6 modulates myofibroblast differentiation at transforming growth factor-β1 transcription level via H2A.Z occupancy and Sp1 recruitment
Si-si Yang et al.
JOURNAL OF CELL SCIENCE (2015)
Heart failure in diabetes: effects of anti-hyperglycaemic drug therapy
Richard E. Gilbert et al.
LANCET (2015)
c-Abl silencing reduced the inhibitory effects of TGF-β1 on apoptosis in systemic sclerosis dermal fibroblasts
Elham Karimizadeh et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice
Guohua Gong et al.
SCIENCE (2015)
Surviving apoptosis: life-death signaling in single cells
Deborah A. Flusberg et al.
TRENDS IN CELL BIOLOGY (2015)
TGF-β1-Mediated Differentiation of Fibroblasts Is Associated with Increased Mitochondrial Content and Cellular Respiration
Ulugbek Negmadjanov et al.
PLOS ONE (2015)
Endothelin-1 signalling controls early embryonic heart rate in vitro and in vivo
S. Karppinen et al.
ACTA PHYSIOLOGICA (2014)
Role for high-glucose-induced protein O-GlcNAcylation in stimulating cardiac fibroblast collagen synthesis
Hugo Aguilar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)
Danshensu Inhibits β-Adrenergic Receptors-Mediated Cardiac Fibrosis by ROS/p38 MAPK Axis
Haiyan Lu et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2014)
Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation
Joyce V. Lee et al.
CELL METABOLISM (2014)
Developmental Heterogeneity of Cardiac Fibroblasts Does Not Predict Pathological Proliferation and Activation
Shah R. Ali et al.
CIRCULATION RESEARCH (2014)
TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice
Shaik O. Rahaman et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis
Thomas Moore-Morris et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Cardiac fibroblast in development and wound healing
Arjun Deb et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes
Sarah M. Williams et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Myofibroblasts: Trust your heart and let fate decide
Jennifer Davis et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
A Reactive Oxygen Species-Mediated, Self-Perpetuating Loop Persistently Activates Platelet-Derived Growth Factor Receptor alpha
Hetian Lei et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
HIP-55/DBNL-dependent regulation of adrenergic receptor mediates the ERK1/2 proliferative pathway
Ning Liu et al.
MOLECULAR BIOSYSTEMS (2014)
Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
Chendong Yang et al.
MOLECULAR CELL (2014)
Remodelling the extracellular matrix in development and disease
Caroline Bonnans et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis
Marlene Kraemer et al.
ANNALS OF THE RHEUMATIC DISEASES (2013)
A 28-kDa Splice Variant of NADPH Oxidase-4 Is Nuclear-Localized and Involved in Redox Signaling in Vascular Cells
Narayana Anilkumar et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
A TRP to cardiac fibroblast differentiation
Charles K. Thodeti et al.
CHANNELS (2013)
Platelet derived growth factor-evoked Ca2+ wave and matrix gene expression through phospholipase C in human pulmonary fibroblast
Subhendu Mukherjee et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Dichloroacetate improves immune dysfunction caused by tumor-secreted lactic acid and increases antitumor immunoreactivity
Toshimitsu Ohashi et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Mitochondrial Reactive Oxygen Species Regulate Transforming Growth Factor-β Signaling
Manu Jain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Calreticulin Regulates Transforming Growth Factor-β-stimulated Extracellular Matrix Production
Kurt A. Zimmerman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Transforming Growth Factor-β1 (TGF-β1)-stimulated Fibroblast to Myofibroblast Differentiation Is Mediated by Hyaluronan (HA)-facilitated Epidermal Growth Factor Receptor (EGFR) and CD44 Co-localization in Lipid Rafts
Adam C. Midgley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
Yong Zhou et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease
Caitlin M. Braitsch et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals
Ravi K. Adapala et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Myofibroblast-mediated mechanisms of pathological remodelling of the heart
Karl T. Weber et al.
NATURE REVIEWS CARDIOLOGY (2013)
TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells
Pasithorn A. Suwanabol et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Excess protein O-GlcNAcylation and the progression of diabetic cardiomyopathy
Eduardo S. Fricovsky et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2012)
Lactic Acid Is Elevated in Idiopathic Pulmonary Fibrosis and Induces Myofibroblast Differentiation via pH-Dependent Activation of Transforming Growth Factor-β
Robert Matthew Kottmann et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Matrix Stiffness-Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction
Xiangwei Huang et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Transforming Growth Factor-β Evokes Ca2+ Waves and Enhances Gene Expression in Human Pulmonary Fibroblasts
Subhendu Mukherjee et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
ß-Adrenergic receptors stimulate interleukin-6 production through Epac-dependent activation of PKCd/p38 MAPK signalling in neonatal mouse cardiac fibroblasts
Chao Chen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Transient Receptor Potential Canonical-3 Channel-Dependent Fibroblast Regulation in Atrial Fibrillation
Masahide Harada et al.
CIRCULATION (2012)
The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors
Asha Acharya et al.
DEVELOPMENT (2012)
A TRPC6-Dependent Pathway for Myofibroblast Transdifferentiation and Wound Healing In Vivo
Jennifer Davis et al.
DEVELOPMENTAL CELL (2012)
Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes
Andre La Gerche et al.
EUROPEAN HEART JOURNAL (2012)
Defining the cellular repertoire of GPCRs identifies a profibrotic role for the most highly expressed receptor, protease-activated receptor 1, in cardiac fibroblasts
Aaron N. Snead et al.
FASEB JOURNAL (2012)
Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism
Yuping Chen et al.
GASTROENTEROLOGY (2012)
Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation
Maria Jesus Perugorria et al.
HEPATOLOGY (2012)
Targeting the TGFβ signalling pathway in disease
Rosemary J. Akhurst et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Potential Adverse Cardiovascular Effects From Excessive Endurance Exercise
James H. O'Keefe et al.
MAYO CLINIC PROCEEDINGS (2012)
Extracellular Matrix and Fibroblast Communication Following Myocardial Infarction
Yonggang Ma et al.
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2012)
Mitochondrial Fission Induces Glycolytic Reprogramming in Cancer-Associated Myofibroblasts, Driving Stromal Lactate Production, and Early Tumor Growth
Carmela Guido et al.
ONCOTARGET (2012)
An Essential Role for Resident Fibroblasts in Experimental Lung Fibrosis Is Defined by Lineage-Specific Deletion of High-Affinity Type II Transforming Growth Factor β Receptor
Rachel K. Hoyles et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Epicardial-Derived Cell Epithelial-to-Mesenchymal Transition and Fate Specification Require PDGF Receptor Signaling
Christopher L. Smith et al.
CIRCULATION RESEARCH (2011)
Diverse patterns of myocardial fibrosis in lifelong, veteran endurance athletes
M. Wilson et al.
JOURNAL OF APPLIED PHYSIOLOGY (2011)
Angiotensin II downregulates catalase expression and activity in vascular adventitial fibroblasts through an AT1R/ERK1/2-dependent pathway
Weiwei Yang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
Intramyocardial Fibroblast Myocyte Communication
Rahul Kakkar et al.
CIRCULATION RESEARCH (2010)
TRPM7-Mediated Ca2+ Signals Confer Fibrogenesis in Human Atrial Fibrillation
Jianyang Du et al.
CIRCULATION RESEARCH (2010)
Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction
Eric M. Small et al.
CIRCULATION RESEARCH (2010)
Smad3 Signaling Critically Regulates Fibroblast Phenotype and Function in Healing Myocardial Infarction
Marcin Dobaczewski et al.
CIRCULATION RESEARCH (2010)
Potential Therapeutic Targets for Cardiac Fibrosis TGFβ, Angiotensin, Endothelin, CCN2, and PDGF, Partners in Fibroblast Activation
Andrew Leask
CIRCULATION RESEARCH (2010)
Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes
Tetsuro Ago et al.
CIRCULATION RESEARCH (2010)
Mitochondrial proton and electron leaks
Martin Jastroch et al.
ESSAYS IN BIOCHEMISTRY: MITOCHONDRIAL FUNCTION (2010)
Oxidative Modification of Nuclear Mitogen-activated Protein Kinase Phosphatase 1 Is Involved in Transforming Growth Factor β1-induced Expression of Plasminogen Activator Inhibitor 1 in Fibroblasts
Rui-Ming Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
Fei Liu et al.
JOURNAL OF CELL BIOLOGY (2010)
The extracellular matrix: At the center of it all
Stephanie L. K. Bowers et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
NAD(P)H Oxidase Mediates TGF-beta 1-Induced Activation of Kidney Myofibroblasts
Corry D. Bondi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Epigenetic Histone Methylation Modulates Fibrotic Gene Expression
Guangdong Sun et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Myocardial remodeling after infarction: the role of myofibroblasts
Susanne W. M. van den Borne et al.
NATURE REVIEWS CARDIOLOGY (2010)
The cell wall polysaccharide metabolism of the brown alga Ectocarpus siliculosus. Insights into the evolution of extracellular matrix polysaccharides in Eukaryotes
Gurvan Michel et al.
NEW PHYTOLOGIST (2010)
O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart
Lewis J. Watson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Modulation of TGFβ1-Dependent Myofibroblast Differentiation by Hyaluronan
Jason Webber et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Abrogation of TGF-β1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
Weichao Guo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signal-regulated kinase in cardiac fibroblasts
Xiuren Gao et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Glutathione redox regulates TGF-β-induced fibrogenic effects through Smad3 activation
Akihiro Ono et al.
FEBS LETTERS (2009)
Hyaluronan Orchestrates Transforming Growth Factor-β1-dependent Maintenance of Myofibroblast Phenotype
Jason Webber et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Inducible Lineage-Specific Deletion of T beta RII in Fibroblasts Defines a Pivotal Regulatory Role during Adult Skin Wound Healing
Christopher P. Denton et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
Louise Hecker et al.
NATURE MEDICINE (2009)
Subcellular localization of Nox4 and regulation in diabetes
Karen Block et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
Kathryn E. Wellen et al.
SCIENCE (2009)
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
Taro Hitosugi et al.
SCIENCE SIGNALING (2009)
Tissue stiffness, latent TGF-β1 Activation, and mechanical signal transduction: Implications for the pathogenesis and treatment of fibrosis
Boris Hinz
Current Rheumatology Reports (2009)
Inhibition of superoxide dismutase induces collagen production in cardiac fibroblasts
Paul Lijnen et al.
AMERICAN JOURNAL OF HYPERTENSION (2008)
Role and regulation of prolyl hydroxylase domain proteins
G-H Fong et al.
CELL DEATH AND DIFFERENTIATION (2008)
Hyaluronan facilitates transforming growth factor-β1-mediated fibroblast proliferation
Soma Meran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
Scott L. Friedman
PHYSIOLOGICAL REVIEWS (2008)
Endothelin is a downstream mediator of profibrotic responses to transforming growth factor β in human lung fibroblasts
Xu Shi-wen et al.
ARTHRITIS AND RHEUMATISM (2007)
Gα12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation
Motohiro Nishida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The myofibroblast - One function, multiple origins
Boris Hinz et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Smooth muscle α-actin expression and myofibroblast differentiation by TGFβ are dependent upon MK2
Anne Marie Sousa et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
IL-1β stimulates rat cardiac fibroblast migration via MAP kinase pathways
M. Darren Mitchell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Glutamine-induced protection of isolated rat heart from ischemia/reperfusion injury is mediated via the hexosamine biosynthesis pathway and increased protein O-GlcNAc levels
Jia Liu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Formation and function of the myofibroblast during tissue repair
Boris Hinz
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)
Gut-enriched Kruppel-like factor interaction with Smad3 inhibits myofibroblast differentiation
Biao Hu et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2007)
Essential role of Smad3 in angiotensin II-induced vascular fibrosis
WS Wang et al.
CIRCULATION RESEARCH (2006)
Adenovirus-mediated overexpression of O-GlcNAcase improves contractile function in the diabetic heart
Y Hu et al.
CIRCULATION RESEARCH (2005)
Adipogenic transcriptional regulation of hepatic stellate cells
HY She et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer
MC Picchio et al.
CLINICAL CANCER RESEARCH (2004)
TGF-β1 and angiotensin networking in cardiac remodeling
S Rosenkranz
CARDIOVASCULAR RESEARCH (2004)
Smad3 null mice develop airspace enlargement and are resistant to TGF-β-mediated pulmonary fibrosis
P Bonniaud et al.
JOURNAL OF IMMUNOLOGY (2004)
Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids
M Montero et al.
BIOCHEMICAL JOURNAL (2004)
Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Spl/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells
MA Alfonso-Jaume et al.
BIOCHEMICAL JOURNAL (2004)
Hyaluronan regulates transforming growth factor-β1 receptor compartmentalization
T Ito et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Induction of vascular smooth muscle α-actin gene transcription in transforming growth factor β1-activated myofibroblasts mediated by dynamic interplay between the pur repressor proteins and Sp1/Smad coactivators
SV Subramanian et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Fibrosis in hypertensive heart disease: role of the renin-angiotensin-aldosterone system
A Gonzalez et al.
MEDICAL CLINICS OF NORTH AMERICA (2004)
Angiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin -: Gq-Gs cross-talk regulates collagen production in cardiac fibroblasts
RS Ostrom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts
J Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Vascular smooth muscle α-actin gene transcription during myofibroblast differentiation requires Sp1/3 protein binding proximal to the MCAT enhancer
JG Cogan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Myofibroblasts and mechano-regulation of connective tissue remodelling
JJ Tomasek et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
TGF-β-induced Ca2+ influx involves the type IIIIP3 receptor and regulates actin cytoskeleton
TA McGowan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)
Identification of novel TGF-β/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach
F Verrecchia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Overexpression of glutamine:fructose-6-phosphate-amidotransferase induces transforming growth factor-β1 synthesis in NIH-3T3 fibroblasts
C Weigert et al.
FEBS LETTERS (2001)
Endothelin-1 stimulates cardiac fibroblast proliferation through activation of protein kinase C
L Piacentini et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2000)
Angiotensin II upregulates transforming growth factor-β type I receptor on rat vascular smooth muscle cells
N Fukuda et al.
AMERICAN JOURNAL OF HYPERTENSION (2000)
Share Paper
