4.5 Article

A Journey toSPSiOL, a New Type of Chiral Ligand Scaffold

Journal

CHINESE JOURNAL OF CHEMISTRY
Volume 38, Issue 10, Pages 1203-1204

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.202000256

Keywords

Spirosilabiindane; Hydrosilation; Ligands; SPSiOL; SPSiPhos

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We report the development of a class of chiral spirosilabiindane scaffoldsviaRh-catalyzed asymmetric double hydrosilation. Enantiopure SPSiOL (spirosilabiindane diol), a new type of chiral building block for preparation of various chiral ligands and catalysts, could be readily prepared on >10-gram scale using this protocol.

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