Related references
Note: Only part of the references are listed.Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo
Dongyuan Wang et al.
CANCER RESEARCH (2019)
Allosteric modulation of sigma receptors by BH3 mimetics ABT-737, ABT-263 (Navitoclax) and ABT-199 (Venetoclax)
John R. Lever et al.
PHARMACOLOGICAL RESEARCH (2019)
A sulfonium tethered peptide ligand rapidly and selectively modifies protein cysteine in vicinity
Dongyuan Wang et al.
CHEMICAL SCIENCE (2019)
Highly Reactive and Tracelessly Cleavable Cysteine-Specific Modification of Proteins via 4-Substituted Cyclopentenone
Jian Yu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Rational Tuning of Fluorobenzene Probes for Cysteine-Selective Protein Modification
Ahmed M. Embaby et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Site-Selective Cysteine-Cyclooctyne Conjugation
Chi Zhang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins
Aline D. de Araujo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma
A. Esteve-Arenys et al.
ONCOGENE (2018)
Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor
Edward P. Harvey et al.
STRUCTURE (2018)
Differential Effects of beta(3)- versus beta(2)-Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived alpha/beta-Peptides
Geoffrey A. Eddinger et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer
Rachel M. Guerra et al.
CELL REPORTS (2018)
In-Tether Chiral Center Induced Helical Peptide Modulators Target p53-MDM2/MDMX and Inhibit Tumor Growth in Stem-Like Cancer Cell (vol 7, pg 4566, 2017)
Kuan Hu et al.
THERANOSTICS (2018)
hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents
Elisa Barile et al.
ACS CHEMICAL BIOLOGY (2017)
Electrophilic Helical Peptides That Bond Covalently, Irreversibly, and Selectively in a Protein-Protein Interaction Site
Aline Dantas de Araujo et al.
ACS MEDICINAL CHEMISTRY LETTERS (2017)
From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors
Avi Ashkenazi et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Selective N-terminal functionalization of native peptides and proteins
Diao Chen et al.
CHEMICAL SCIENCE (2017)
Practical Chemical Synthesis of Atypical Ubiquitin Chains by Using an Isopeptide-Linked Ub Isomer
Shan Tang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
PDZ-Reactive Peptide Activates Ephrin-B Reverse Signaling and Inhibits Neuronal Chemotaxis
Yongsheng Yu et al.
ACS CHEMICAL BIOLOGY (2016)
Site-selective protein-modification chemistry for basic biology and drug development
Nikolaus Krall et al.
NATURE CHEMISTRY (2016)
The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism
Mary Ann Anderson et al.
BLOOD (2016)
Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies
Alex R. D. Delbridge et al.
NATURE REVIEWS CANCER (2016)
Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors
Annissa J. Huhn et al.
CELL CHEMICAL BIOLOGY (2016)
Role of the pro-survival molecule Bfl-1 in melanoma
C. K. Hind et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)
The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics
Aaron N. Hata et al.
CANCER DISCOVERY (2015)
Chemical Biology Strategies for Posttranslational Control of Protein Function
Rishi Rakhit et al.
CHEMISTRY & BIOLOGY (2014)
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
Peter E. Czabotar et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Selective chemical protein modification
Christopher D. Spicer et al.
NATURE COMMUNICATIONS (2014)
MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R
J. Gong et al.
ONCOGENE (2013)
Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease
Andrew W. Roberts et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin
Bijan Zakeri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Prognostic significance of Bcl-xL gene expression in human colorectal cancer
Jin-Song Yang et al.
ACTA HISTOCHEMICA (2011)
miR-193b Regulates Mcl-1 in Melanoma
Jiamin Chen et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Choosing an effective protein bioconjugation strategy
Nicholas Stephanopoulos et al.
NATURE CHEMICAL BIOLOGY (2011)
Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2
Jason R. Porter et al.
CHEMICAL COMMUNICATIONS (2010)
Protein Chemical Modification on Endogenous Amino Acids
Emmanuel Basle et al.
CHEMISTRY & BIOLOGY (2010)
Selective Covalent Labeling of Tag-Fused GPCR Proteins on Live Cell Surface with a Synthetic Probe for Their Functional Analysis
Hiroshi Nonaka et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
Wyndham H. Wilson et al.
LANCET ONCOLOGY (2010)
The landscape of somatic copy-number alteration across human cancers
Rameen Beroukhim et al.
NATURE (2010)
Dynamical Binding of Hydrogen-Bond Surrogate Derived Bak Helices to Antiapoptotic Protein Bcl-xL
Ju Bao et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia
Victoria Del Gaizo Moore et al.
BLOOD (2008)
Non-enzymatic covalent protein labeling using a reactive tag
Hiroshi Nonaka et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Functional validation of the analplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes
Roberto Piva et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
miR-15 and miR-16 induce apoptosis by targeting BCL2
A Cimmino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Chimeric (α/β plus α)-peptide ligands for the BH3-recognition cleft of Bcl-xL:: Critical role of the molecular scaffold in protein surface recognition
JD Sadowsky et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
High expression of bfl-1 contributes to the apoptosis resistant phenotype in B-cell chronic lymphocytic leukemia
AA Morales et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Antibodies with infinite affinity
AJ Chmura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)