Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 128, Issue -, Pages -Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2020.110352
Keywords
Herbal medicine; Akkermansia. muciniphila; Prebiotics; Gut microbiota; Type 2 diabetes mellitus; Cardiovascular diseases; Liver diseases; Intestinal diseases; Neuropsychiatric diseases
Funding
- National Natural Science Foundation of China [81573978]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Key Talents Training Program of Chinese Medicine in Jiangsu Province [SLJ0203]
- Graduate student scientific research innovation projects in Jiangsu province [SJKY19_1401]
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There are trillions and trillions of microorganisms in the human gut, and these microorganisms and their metabolites are closely related to human health. Recent studies have found that the abundance of Akkermansia muciniphila is decreased in many diseases. Supplementation of A. muciniphila is used to treat many diseases, suggesting it as a probiotic. Herbal medicines are considered as valuable asset of traditional Chinese medicine. Recent studies have revealed traditional Chinese medicine as a potential prebiotic agent for the treatment of many diseases. Hence, in this review, we aimed to provide a plausible mechanistic basis for the interactions between herbal medicines and A. muciniphila, and therapeutic benefits on this interaction in various illnesses.
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