Journal
BIOINFORMATICS
Volume 37, Issue 7, Pages 1026-1028Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btaa713
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Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico [457851/2014-7]
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior [051/2013]
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CONAN is a web application developed for detecting specificity determinants and function-related sites through amino acids co-variation networks analysis, with a focus on local coevolutionary constraints. The software enables the characterization of structurally and functionally relevant residue groups by automatically cross-referencing with GO terms, UniprotKb annotations, and INTERPRO.
A Summary: CONAN is a web application developed to detect specificity determinants and function-related sites by amino acids co-variation networks analysis, emphasizing local coevolutionary constraints. The software allows the characterization of structurally and functionally relevant groups of residues and their relationship with subsets of sequences by automatic cross-referencing with GO terms, UniprotKb annotations and INTERPRO.
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