4.2 Article

Frontiers in hemodialysis: Innovations and technological advances

Journal

ARTIFICIAL ORGANS
Volume 45, Issue 2, Pages 175-182

Publisher

WILEY
DOI: 10.1111/aor.13798

Keywords

bioartificial kidney; convection; expanded hemodialysis; graphene oxide membrane; hemodialysis; incremental; medium cut-off membrane; mixed matrix membrane; online hemodiafiltration; wearable artificial kidney

Funding

  1. Biomedical Materials institute (Project BioKid - Dutch Ministry of Economic Affairs)
  2. Marie Curie ITN project: BIOART [EU-FP7-PEOPLE-ITN-2012]
  3. Dutch Kidney Foundation
  4. EUTox working group of the European society of European Society for artificial organs
  5. HealthHolland KidneyPort [40-43100-98-009]
  6. EPSRC [EP/K005014/1] Funding Source: UKRI

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In response to the increasing demand for hemodialysis treatment, efforts are being made to seek new therapeutic approaches and technological innovations, including the development of dialyzers with improved characteristics and wearable technology. The development of more accurate kinetic models, novel HD membranes using nanotechnology, and the latest technology in materials science have enabled the introduction of novel solutions that are already on the market or close to being commercially available.
As increasing demand for hemodialysis (HD) treatment incurs significant financial burden to healthcare systems and ecological burden as well, novel therapeutic approaches as well as innovations and technological advances are being sought that could lead to the development of purification devices such as dialyzers with improved characteristics and wearable technology. Novel knowledge such as the development of more accurate kinetic models, the development of novel HD membranes with the use of nanotechnology, novel manufacturing processes, and the latest technology in the science of materials have enabled novel solutions already marketed or on the verge of becoming commercially available. This collaborative article reviews the latest advances in HD as they were presented by the authors in a recent symposium titled Frontiers in Haemodialysis, held on 12th December 2019 at the Royal Society of Medicine in London.

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