Journal
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume 104, Issue 18, Pages 7767-7775Publisher
SPRINGER
DOI: 10.1007/s00253-020-10813-7
Keywords
Biorefinery; Cellulosic biomass utilization; Enzymatic conversion; Levulinic acid; Microbial conversion
Categories
Funding
- Institute for Fermentation, Osaka, Japan
Ask authors/readers for more resources
Levulinic acid (LA) is an important chemical building block listed among the top 12 value-added chemicals by the United States Department of Energy, and can be obtained through the hydrolysis of lignocellulosic biomass. Using the same approach as in the catalytic production of LA from biomass, catalytic methods to upgrade LA to higher value chemicals have been investigated. Since the discovery of the catabolic genes and enzymes in the LA metabolic pathway, bioconversion of LA into useful chemicals has attracted attention, and can potentially broaden the range of biochemical products derived from cellulosic biomass. With a brief introduction to the LA catabolic pathway inPseudomonasspp., this review summarizes the current studies on the microbial conversion of LA into bioproducts, including the recent developments to achieve higher yields through genetic engineering ofEscherichia colicells. Three different types of reactions during the enzymatic conversion of LA are also discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available