4.4 Review

Recent Advances in the Coupling Reactions of Arylhydrazine via C-N Bond Cleavage

Journal

CHINESE JOURNAL OF ORGANIC CHEMISTRY
Volume 36, Issue 8, Pages 1790-1796

Publisher

SCIENCE PRESS
DOI: 10.6023/cjoc201601037

Keywords

C-N bond cleavage; aryl hydrazine; coupling reaction; radical

Funding

  1. National Natural Science Foundation of China [21502075, 21502069, 201502069]
  2. National Natural Science Foundation of Zhejiang Province [LQ15B020006]
  3. Foundation from Zhejiang Education Department [Y201431173]
  4. National Natural Science Foundation of China [21502075, 21502069, 201502069]
  5. National Natural Science Foundation of Zhejiang Province [LQ15B020006]
  6. Foundation from Zhejiang Education Department [Y201431173]

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As a special synthons containing C-N bond, hydrazine chemistry has attracted a growing interest of chemists due to its versatility in cross-coupling arylation. This review summarizes the recent advances in the coupling reactions of arylhydrazine, which is utilized as an effective arylation reagent in radical reactions, and transition metal-catalyzed homocoupling, Suzuki coupling and Heck coupling via C-N bond cleavage.

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