Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 59, Issue 40, Pages 17614-17621Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.202006392
Keywords
anion transport; gold complexes; molecular switch; reduction kinetics; supramolecular chemistry
Categories
Funding
- Australian Research Council [DP200100453]
- University of Sydney
- University of Wollongong
- Australian Research Council [DP200100453] Funding Source: Australian Research Council
Ask authors/readers for more resources
Anion transporters have shown potential application as anti-cancer agents that function by disrupting homeostasis and triggering cell death. In this research article we report switchable anion transport by gold complexes of anion transporters that are switched on in situ in the presence of the reducing agent GSH by decomplexation of gold. GSH is found in higher concentrations in tumors than in healthy tissue and hence this approach offers a strategy to target these systems to tumors.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
