4.5 Review

Effects of Diet on Acne and Its Response to Treatment

Journal

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
Volume 22, Issue 1, Pages 55-65

Publisher

ADIS INT LTD
DOI: 10.1007/s40257-020-00542-y

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Funding

  1. Sun Pharmaceutical Industries, Inc.

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Our understanding of the pathogenesis of acne vulgaris is continuously evolving, with factors such as genetics, hormones, inflammation, and environment playing a significant role. Diet has been a longstanding topic of discussion in acne pathophysiology, particularly in terms of glycemic load, dairy consumption, and fatty acid intake. Studies have shown potential benefits of probiotics and omega-3 fatty acids in individuals with acne, suggesting a need for further research in these areas.
Our understanding of the pathogenesis of acne vulgaris is still evolving. It is known that multiple factors impact acne pathophysiology, including genetic, hormonal, inflammatory, and environmental influences. Because of its implications in many of these factors, diet has been a part of the acne discussion for decades. Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and gamma-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies. In this review, we discuss the current evidence regarding the diets of US patients with acne and how they may impact acne and acne treatment.

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