Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 362, Issue 19, Pages 4010-4026Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.202000608
Keywords
organocatalyst; benzannulation; metal-free; multi-substituted arenes
Categories
Funding
- National Natural Science Foundation of China [21702189, 21971224]
- Key scientific and technological project of Henan Province [202102310004]
- China Postdoctoral Science Foundation [2017M610458, 2018T110737, 2019M652561]
- Postdoctoral Research Grant in Henan Province [001701006]
- Henan Agricultural University
- Zhengzhou University of China
Ask authors/readers for more resources
Aromatic compounds are omnipresent in organic chemistry, which are the broadest skeletons of bioactive molecules, medicines, and materials. Due to their importance, conventional methods to assemble aromatic rings have attracted considerable attention. The direct formation of benzene cores from readily available acyclic precursors offers a highly versatile and superior approach to prepare both small organic molecules and sophisticated natural products. Recently, organocatalyst-mediated annulation reaction, including phosphine-, tertiary amine-, secondary amine-, primary amine-, and NHC-mediated benzannulation reactions, is considered as an efficient method to access multi-substituted arenes. In this review, we will emphasize the selected examples of organocatalyst-mediated benzannulation reactions of available acyclic precursors for the construction of diverse aromatics.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available