4.7 Review

Catalytic Strategies for the Asymmetric Construction of Cyclic Frameworks with a Halogenated Tetrasubstituted Stereocenter

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 362, Issue 19, Pages 3926-3947

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.202000540

Keywords

asymmetric synthesis; halogenated stereocenters; organocatalysis; metal catalysis; cyclic structure

Funding

  1. National Natural Science Foundation of China [81703809, 21871031, 21702021]
  2. Science & Technology Department of Sichuan Province [2017JQ0032]
  3. Thousand Talents Program of Sichuan Province
  4. Chengdu Talents Program
  5. Scientific Fund of Sichuan Provincial Education Department [18ZA0128, 18ZA0127]

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The efficient and enantioselective construction of cyclic compounds with a halogenated tetrasubstituted carbon through various catalytic strategies remains challenging. Thus, research on modern asymmetric catalysis is important. In this review, recent achievements that streamlined the synthesis of halogenated cyclic molecules through organocatalysis or transition-metal catalysis were introduced.

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