Journal
ACS NANO
Volume 14, Issue 7, Pages 8247-8256Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.0c01705
Keywords
micromotors; self-propulsion; surface walker; magnetic field; cancer treatment
Categories
Funding
- project Advanced Functional Nanorobots (EFRR) [CZ.02.1.01/0.0/0.0/15_003/0000444]
Ask authors/readers for more resources
The actuation of micro/nanomachines by means of a magnetic field is a promising fuel-free way to transport cargo in microscale dimensions. This type of movement has been extensively studied for a variety of micro/nanomachine designs, and a special magnetic field configuration results in a near-surface walking. We developed walking micromachines which transversally move in a magnetic field, and we used them as microrobotic scalpels to enter and exit an individual cancer cell and cut a small cellular fragment. In these microscalpels, the center of mass lies approximately in the middle of their length. The microrobotic scalpels show good propulsion efficiency and high step-out frequencies of the magnetic field. Au/Ag/Ni microrobotic scalpels controlled by a transversal rotating magnetic field can enter the cytoplasm of cancer cells and also are able to remove a piece of the cytosol while leaving the cytoplasmic membrane intact in a microsurgery-like manner. We believe that this concept can be further developed for potential biological or medical applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available