Journal
FOODS
Volume 9, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/foods9030340
Keywords
resveratrol; bioactivities; anticancer; anti-obesity; antidiabetes; molecular mechanisms
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Funding
- China Central Public-interest Scientific Institution Basal Research Fund [Y2020XK05]
- National Key RAMP
- D Program of China [2018YFC1604400]
- Key Project of Guangdong Provincial Science and Technology Program [2014B020205002]
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Resveratrol is a bioactive compound in many foods. Since its anticancer activity was reported in 1997, its health benefits have been intensively investigated. Resveratrol has antioxidant, anti-inflammatory, immunomodulatory, glucose and lipid regulatory, neuroprotective, and cardiovascular protective effects, therefore, can protect against diverse chronic diseases, such as cardiovascular diseases (CVDs), cancer, liver diseases, obesity, diabetes, Alzheimer's disease, and Parkinson's disease. This review summarizes the main findings of resveratrol-related health benefits in recent epidemiological surveys, experimental studies, and clinical trials, highlighting its related molecular mechanisms. Resveratrol, therefore, has been regarded as a potent candidate for the development of nutraceuticals and pharmaceuticals to prevent and treat certain chronic diseases.
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