Journal
ANNALS OF TRANSLATIONAL MEDICINE
Volume 8, Issue 8, Pages -Publisher
AME PUBL CO
DOI: 10.21037/atm.2020.03.218
Keywords
Mesenchymal stem cells (MSCs); liver disease; cirrhosis
Categories
Funding
- National Natural Science Foundation of China [NSFC: 81721091]
Ask authors/readers for more resources
Liver disease is a major health issue which present poor clinical treatment performance. Cirrhosis and liver failure are common clinical manifestations of liver diseases. Liver transplantation is recognized as the ultimate and most efficient therapy to the end stage of liver disease. But it was limited by the shortage of honor organs and high cost. Nowadays, stem cell therapy gained more and more attention due to its attractive efficacy in treating liver disease especially in cirrhosis during the clinical trials. Mesenchymal stem cell (MSC) can be differentiated into hepatocytes, promote liver regeneration, inhibit liver fibrosis and induce liver apoptosis, particularly via paracrine mechanisms. This review will highlight recent clinical applications of MSC, providing the available evidence and discussing some unsolved questions in treating liver disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available