Related references
Note: Only part of the references are listed.Role of Wdr45b in maintaining neural autophagy and cognitive function
Cuicui Ji et al.
AUTOPHAGY (2020)
The ATG conjugation systems in autophagy
Noboru Mizushima
CURRENT OPINION IN CELL BIOLOGY (2020)
BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation
Mark A. Lampert et al.
AUTOPHAGY (2019)
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
Evandro F. Fang et al.
NATURE NEUROSCIENCE (2019)
Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy
Nabil Eid et al.
CELLS (2019)
A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities
Musharraf Jelani et al.
BRAIN (2019)
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform
Maria Zachari et al.
DEVELOPMENTAL CELL (2019)
Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
Ricardo Aparicio et al.
CELL REPORTS (2019)
Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
Andrea K. H. Stavoe et al.
ELIFE (2019)
Dysregulated autophagy as a new aspect of the molecular pathogenesis of Krabbe disease
Ambra Del Grosso et al.
NEUROBIOLOGY OF DISEASE (2019)
Mitochondria-Striking a balance between host and endosymbiont
Richard J. Youle
SCIENCE (2019)
Functional Transcriptome Analysis in ARSACS KO Cell Model Reveals a Role of Sacsin in Autophagy
Federica Morani et al.
SCIENTIFIC REPORTS (2019)
Biological Functions of Autophagy Genes: A Disease Perspective
Beth Levine et al.
CELL (2019)
Miro proteins prime mitochondria for Parkin translocation and mitophagy
Dzhamilja Safiulina et al.
EMBO JOURNAL (2019)
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy
Jonathan P. Bernardini et al.
EMBO JOURNAL (2019)
Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses
Anil B. Mukherjee et al.
MOLECULAR NEURODEGENERATION (2019)
Impaired autophagic and mitochondrial functions are partially restored by ERT in Gaucher and Fabry diseases
Margarita M. Ivanova et al.
PLOS ONE (2019)
AUTACs: Cargo-Specific Degraders Using Selective Autophagy
Daiki Takahashi et al.
MOLECULAR CELL (2019)
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
Penelope A. Andreux et al.
NATURE METABOLISM (2019)
Mitochondrial Dysfunction in Parkinson's Disease-Cause or Consequence?
Chun Chen et al.
BIOLOGY-BASEL (2019)
Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline
Claudia Schwarz et al.
AGING-US (2018)
Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy
Arthur F. Kluge et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication
Andrew Melber et al.
CELL RESEARCH (2018)
Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance
Allyson L. Anding et al.
CURRENT BIOLOGY (2018)
Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance
Sarah Pickles et al.
CURRENT BIOLOGY (2018)
Degradation of altered mitochondria by autophagy is impaired in Lafora disease
Marcos Lahuerta et al.
FEBS JOURNAL (2018)
Impaired mitochondrial dynamics underlie axonal defects in hereditary spastic paraplegias
Kyle Denton et al.
HUMAN MOLECULAR GENETICS (2018)
Spermidine in health and disease
Frank Madeo et al.
SCIENCE (2018)
Role of Optineurin in the Mitochondrial Dysfunction: Potential implications in Neurodegenerative Diseases and Cancer
Robert Weil et al.
FRONTIERS IN IMMUNOLOGY (2018)
Iron overload is accompanied by mitochondrial and lysosomal dysfunction in WDR45 mutant cells
Philip Seibler et al.
BRAIN (2018)
Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
Konstantinos Palikaras et al.
NATURE CELL BIOLOGY (2018)
HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα
Anthea Di Rita et al.
NATURE COMMUNICATIONS (2018)
Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy
Eleonora Napoli et al.
SCIENTIFIC REPORTS (2018)
Mitochondrial genetic medicine
Douglas C. Wallace
NATURE GENETICS (2018)
Lysosomal storage diseases
Frances M. Platt et al.
NATURE REVIEWS DISEASE PRIMERS (2018)
PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation
So Young Eun et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
WDR45B-related intellectual disability, spastic quadriplegia, epilepsy, and cerebral hypoplasia: A consistent neurodevelopmental syndrome
J. Suleiman et al.
CLINICAL GENETICS (2018)
Peroxisomal protein PEX13 functions in selective autophagy
Ming Y. Lee et al.
EMBO REPORTS (2017)
Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations
Chunyan Liao et al.
NEUROLOGY (2017)
Parkin and mitophagy in cancer
J. P. Bernardini et al.
ONCOGENE (2017)
Mitochondrial fission facilitates the selective mitophagy of protein aggregates
Jonathon L. Burman et al.
JOURNAL OF CELL BIOLOGY (2017)
mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy
Rosa Bartolomeo et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Impaired mitophagy facilitates mitochondrial damage in Danon disease
Sherin I. Hashem et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2017)
Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway
Francois Le Guerroue et al.
MOLECULAR CELL (2017)
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
Lorenzo Galluzzi et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Mitophagy in neurodegeneration and aging
Elayne M. Fivenson et al.
NEUROCHEMISTRY INTERNATIONAL (2017)
Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C-elegans lifespan
Chensu Wang et al.
NATURE COMMUNICATIONS (2017)
WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy
Daniela Bakula et al.
NATURE COMMUNICATIONS (2017)
Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster
Anil Rana et al.
NATURE COMMUNICATIONS (2017)
Autophagy and Mitophagy in Cardiovascular Disease
Jose Manuel Bravo-San Pedro et al.
CIRCULATION RESEARCH (2017)
Modulation of mTOR signaling as a strategy for the treatment of Pompe disease
Jeong-A Lim et al.
EMBO MOLECULAR MEDICINE (2017)
The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species
Evan A. Bordt et al.
DEVELOPMENTAL CELL (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
Mammalian Mitochondria and Aging: An Update
Timo E. S. Kauppila et al.
CELL METABOLISM (2017)
Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy
Davor Ivankovic et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy
Ming Chen et al.
AUTOPHAGY (2016)
New genes and pathomechanisms in mitochondrial disorders unraveled by NGS technologies
Andrea Legati et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2016)
Fanconi Anemia Proteins Function in Mitophagy and Immunity
Rhea Sumpter et al.
CELL (2016)
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Evandro Fei Fang et al.
CELL METABOLISM (2016)
Selective mitochondrial depletion, apoptosis resistance, and increased mitophagy in human Charcot-Marie-Tooth 2A motor neurons
Federica Rizzo et al.
HUMAN MOLECULAR GENETICS (2016)
A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay
Teisha Y. Bradshaw et al.
HUMAN MOLECULAR GENETICS (2016)
Mitochondrial dysfunction in Parkinson's disease
Anindita Bose et al.
JOURNAL OF NEUROCHEMISTRY (2016)
The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes
Zheng Wang et al.
MOLECULAR CELL (2016)
The Mitochondrial Basis of Aging
Nuo Sun et al.
MOLECULAR CELL (2016)
Autophagy maintains stemness by preventing senescence
Laura Garcia-Prat et al.
NATURE (2016)
Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents
Dongryeol Ryu et al.
NATURE MEDICINE (2016)
Cardioprotection and lifespan extension by the natural polyamine spermidine
Tobias Eisenberg et al.
NATURE MEDICINE (2016)
Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
Benjamin Richter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
Erin Quan Toyama et al.
SCIENCE (2016)
Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome
Michal Cagalinec et al.
PLOS BIOLOGY (2016)
Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay
Myungjin Kim et al.
ELIFE (2016)
ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts
Yongmei Qi et al.
SCIENTIFIC REPORTS (2016)
Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease
Cyril Pottier et al.
ACTA NEUROPATHOLOGICA (2015)
Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy
Paul Hsu et al.
AUTOPHAGY (2015)
The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis
Yan G. Zhao et al.
AUTOPHAGY (2015)
Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways
Yuko Hirota et al.
AUTOPHAGY (2015)
Mitochondrial DNA Variation in Human Radiation and Disease
Douglas C. Wallace
CELL (2015)
Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans
Alfonso Schiavi et al.
CURRENT BIOLOGY (2015)
Defective autophagy through epg5 mutation results in failure to reduce germ plasm and mitochondria
Amaury Herpin et al.
FASEB JOURNAL (2015)
MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5
Catherine L. Nezich et al.
JOURNAL OF CELL BIOLOGY (2015)
Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1-Nrf2 Protein-Protein Interaction
Helene C. Bertrand et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin
Almas Siddiqui et al.
JOURNAL OF NEUROSCIENCE (2015)
Measuring In Vivo Mitophagy
Nuo Sun et al.
MOLECULAR CELL (2015)
Coordination of mitophagy and mitochondrial biogenesis during ageing in C-elegans
Konstantinos Palikaras et al.
NATURE (2015)
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Michael Lazarou et al.
NATURE (2015)
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
Axel Freischmidt et al.
NATURE NEUROSCIENCE (2015)
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
Elizabeth T. Cirulli et al.
SCIENCE (2015)
Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
Brent J. Ryan et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Spermidine induces autophagy by inhibiting the acetyltransferase EP300
F. Pietrocola et al.
CELL DEATH AND DIFFERENTIATION (2015)
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
Tobias Wauer et al.
EMBO JOURNAL (2015)
Zellweger syndrome and secondary mitochondrial myopathy
Vincenzo Salpietro et al.
EUROPEAN JOURNAL OF PEDIATRICS (2015)
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
Agne Kazlauskaite et al.
BIOCHEMICAL JOURNAL (2014)
Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction
Evandro Fei Fang et al.
CELL (2014)
A High-Fat Diet and NAD+ Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome
Morten Scheibye-Knudsen et al.
CELL METABOLISM (2014)
PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy
Daniel A. East et al.
CHEMISTRY & BIOLOGY (2014)
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
Gian-Luca McLelland et al.
EMBO JOURNAL (2014)
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Lesley A. Kane et al.
JOURNAL OF CELL BIOLOGY (2014)
Downregulation of E3 Ubiquitin Ligases and Mitophagy-Related Genes in Skeletal Muscle of Physically Inactive, Frail Older Women: A Cross-Sectional Comparison
Micah J. Drummond et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12-5-16L1
Hannah C. Dooley et al.
MOLECULAR CELL (2014)
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
Alban Ordureau et al.
MOLECULAR CELL (2014)
Ubiquitin is phosphorylated by PINK1 to activate parkin
Fumika Koyano et al.
NATURE (2014)
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
Baris Bingol et al.
NATURE (2014)
Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
Yvette C. Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes
Shinya Honda et al.
NATURE COMMUNICATIONS (2014)
Recent Mitochondrial DNA Mutations Increase the Risk of Developing Common Late-Onset Human Diseases
Gavin Hudson et al.
PLOS GENETICS (2014)
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
Koji Yamano et al.
ELIFE (2014)
A novel diagnostic tool reveals mitochondrial pathology in human diseases and aging
Morten Scheibye-Knudsen et al.
AGING-US (2013)
PINK1 is degraded through the N-end rule pathway
Koji Yamano et al.
AUTOPHAGY (2013)
Defective autophagy in spastizin mutated patients with hereditary spastic paraparesis type 15
Chiara Vantaggiato et al.
BRAIN (2013)
Beta-propeller protein-associated neurodegeneration: a new X-linked dominant disorder with brain iron accumulation
Susan J. Hayflick et al.
BRAIN (2013)
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Laurent Mouchiroud et al.
CELL (2013)
Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease-Links to Parkinson's Disease
Laura D. Osellame et al.
CELL METABOLISM (2013)
A Mitochondrial Ribosomal and RNA Decay Pathway Blocks Cell Proliferation
Uwe Richter et al.
CURRENT BIOLOGY (2013)
Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease
Carmine Spampanato et al.
EMBO MOLECULAR MEDICINE (2013)
Comprehensive next-generation sequence analyses of the entire mitochondrial genome reveal new insights into the molecular diagnosis of mitochondrial DNA disorders
Hong Cui et al.
GENETICS IN MEDICINE (2013)
Parkin-catalyzed Ubiquitin-Ester Transfer Is Triggered by PINK1-dependent Phosphorylation
Masahiro Iguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration
Hongyu Zhao et al.
JOURNAL OF CELL BIOLOGY (2013)
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
Shireen A. Sarraf et al.
NATURE (2013)
Mitonuclear protein imbalance as a conserved longevity mechanism
Riekelt H. Houtkooper et al.
NATURE (2013)
Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy
Thomas Cullup et al.
NATURE GENETICS (2013)
De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood
Hirotomo Saitsu et al.
NATURE GENETICS (2013)
Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
Anil Rana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
Yun Chen et al.
SCIENCE (2013)
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
Atsushi Hoshino et al.
NATURE COMMUNICATIONS (2013)
Mutation in TECPR2 Reveals a Role for Autophagy in Hereditary Spastic Paraparesis
Danit Oz-Levi et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
Exome Sequencing Reveals De Novo WDR45 Mutations Causing a Phenotypically Distinct, X-Linked Dominant Form of NBIA
Tobias B. Haack et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
Autophagy and mitochondria in Pompe disease: Nothing is so new as what has long been forgotten
Nina Raben et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2012)
Genetics and molecular basis of human peroxisome biogenesis disorders
Hans R. Waterham et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
Nathan L. Price et al.
CELL METABOLISM (2012)
A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
Vincent Soubannier et al.
CURRENT BIOLOGY (2012)
Expression of Pink1 with α-synuclein in the dopaminergic neurons of Drosophila leads to increases in both lifespan and healthspan
A. M. Todd et al.
GENETICS AND MOLECULAR RESEARCH (2012)
Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1
M. Paulina Ordonez et al.
HUMAN MOLECULAR GENETICS (2012)
Impaired proteolysis underlies autophagic dysfunction in Niemann-Pick type C disease
Matthew J. Elrick et al.
HUMAN MOLECULAR GENETICS (2012)
Voltage-dependent Anion Channels (VDACs) Recruit Parkin to Defective Mitochondria to Promote Mitochondrial Autophagy
Yu Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
Morten Scheibye-Knudsen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
Lei Liu et al.
NATURE CELL BIOLOGY (2012)
Mitochondrial Fission, Fusion, and Stress
Richard J. Youle et al.
SCIENCE (2012)
Molecular Diagnosis of Infantile Mitochondrial Disease with Targeted Next-Generation Sequencing
Sarah E. Calvo et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Characterization of Mitophagy in the 6-Hydoxydopamine Parkinson's Disease Model
Maria E. Solesio et al.
TOXICOLOGICAL SCIENCES (2012)
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
Kahori Shiba-Fukushima et al.
SCIENTIFIC REPORTS (2012)
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
Chandana Kondapalli et al.
OPEN BIOLOGY (2012)
SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
Faisal Fecto et al.
ARCHIVES OF NEUROLOGY (2011)
PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
Xinnan Wang et al.
CELL (2011)
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress
L. Bouman et al.
CELL DEATH AND DIFFERENTIATION (2011)
Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis
Yun Chen et al.
CIRCULATION RESEARCH (2011)
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Emma Deas et al.
HUMAN MOLECULAR GENETICS (2011)
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
Cathrin Meissner et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
Daniel F. Egan et al.
SCIENCE (2011)
Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder-murine Pompe disease
Nina Raben et al.
AUTOPHAGY (2010)
Autophagosome maturation is impaired in Fabry disease
Marc Chevrier et al.
AUTOPHAGY (2010)
Multi-system neurological disease is common in patients with OPA1 mutations
P. Yu-Wai-Man et al.
BRAIN (2010)
Nix is a selective autophagy receptor for mitochondrial clearance
Ivana Novak et al.
EMBO REPORTS (2010)
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
Matthew E. Gegg et al.
HUMAN MOLECULAR GENETICS (2010)
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
I. Irrcher et al.
HUMAN MOLECULAR GENETICS (2010)
Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1
Mei Cui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
Atsushi Tanaka et al.
JOURNAL OF CELL BIOLOGY (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Seok Min Jin et al.
JOURNAL OF CELL BIOLOGY (2010)
Mutations of optineurin in amyotrophic lateral sclerosis
Hirofumi Maruyama et al.
NATURE (2010)
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Sven Geisler et al.
NATURE CELL BIOLOGY (2010)
Genotype-Phenotype Correlations in Charcot-Marie-Tooth Disease Type 2 Caused by Mitofusin 2 Mutations
Judith Calvo et al.
ARCHIVES OF NEUROLOGY (2009)
Inhibition of autophagosome formation restores mitochondrial function in mucolipidosis II and III skin fibroblasts
Takanobu Otomo et al.
MOLECULAR GENETICS AND METABOLISM (2009)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Canto et al.
NATURE (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
OPA1 Deficiency Associated with Increased Autophagy in Retinal Ganglion Cells in a Murine Model of Dominant Optic Atrophy
Kathryn E. White et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization
Ann Cassidy-Stone et al.
DEVELOPMENTAL CELL (2008)
Essential role for Nix in autophagic maturation of erythroid cells
Hector Sandoval et al.
NATURE (2008)
A block of autophagy in lysosomal storage disorders
Carmine Settembre et al.
HUMAN MOLECULAR GENETICS (2008)
NIX is required for programmed mitochondrial clearance during reticulocyte maturation
Rachel L. Schweers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mitochondrial disease: A practical approach for primary care physicians
Richard H. Haas et al.
PEDIATRICS (2007)
Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects
Chris D. Pacheco et al.
HUMAN MOLECULAR GENETICS (2007)
Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease
Mark W. Dodson et al.
CURRENT OPINION IN NEUROBIOLOGY (2007)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara et al.
NATURE (2006)
Uth1p is involved in the autophagic degradation of mitochondria
I Kissová et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The role of autophagy during the early neonatal starvation period
A Kuma et al.
NATURE (2004)
WIPI-1α (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy
T Proikas-Cezanne et al.
ONCOGENE (2004)
Parkinsonism among Gaucher disease carriers
O Goker-Alpan et al.
JOURNAL OF MEDICAL GENETICS (2004)
Glucocerebrosidase mutations in subjects with parkinsonism
A Lwin et al.
MOLECULAR GENETICS AND METABOLISM (2004)
Premature ageing in mice expressing defective mitochondrial DNA polymerase
A Trifunovic et al.
NATURE (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)
E Baumgart et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
Y Tanaka et al.
NATURE (2000)
Share Paper
