Related references
Note: Only part of the references are listed.PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis
Chaojun Yan et al.
AUTOPHAGY (2020)
Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate
Kaili Ma et al.
CELL DEATH AND DIFFERENTIATION (2020)
Recruitment and Activation of the ULK1/Atg1 Kinase Complex in Selective Autophagy
Eleonora Turco et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy
Flavie Strappazzon et al.
CELL DEATH AND DIFFERENTIATION (2020)
Resveratrol Activates Neuronal Autophagy Through AMPK in the Ischemic Brain
Narayana Pineda-Ramirez et al.
MOLECULAR NEUROBIOLOGY (2020)
FUN14 Domain-Containing 1-Mediated Mitophagy Suppresses Hepatocarcinogenesis by Inhibition of Inflammasome Activation in Mice
Wenhui Li et al.
HEPATOLOGY (2019)
BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation
Mark A. Lampert et al.
AUTOPHAGY (2019)
Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential
Frank Madeo et al.
CELL METABOLISM (2019)
The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria
Benjamin J. Ravenhill et al.
MOLECULAR CELL (2019)
Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy
Jose Norberto S. Vargas et al.
MOLECULAR CELL (2019)
FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates
Eleonora Turco et al.
MOLECULAR CELL (2019)
Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing
Yifan Zhang et al.
NATURE IMMUNOLOGY (2019)
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
Evandro F. Fang et al.
NATURE NEUROSCIENCE (2019)
LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy
Benjamin Scott Padman et al.
NATURE COMMUNICATIONS (2019)
The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
Didac Carmona-Gutierrez et al.
NATURE COMMUNICATIONS (2019)
Inflammation, Infectious Triggers, and Parkinson's Disease
Elisa Caggiu et al.
FRONTIERS IN NEUROLOGY (2019)
Urolithin A-activated autophagy but not mitophagy protects against ischemic neuronal injury by inhibiting ER stress in vitro and in vivo
Anil Ahsan et al.
CNS NEUROSCIENCE & THERAPEUTICS (2019)
NIPSNAP1 and NIPSNAP2 Act as Eat Me Signals for Mitophagy
Yakubu Princely Abudu et al.
DEVELOPMENTAL CELL (2019)
Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline
Toby Lieber et al.
NATURE (2019)
Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury
Wenjun Xiong et al.
FRONTIERS IN PHYSIOLOGY (2019)
Fndc-1 contributes to paternal mitochondria elimination in C. elegans
Yunki Lim et al.
DEVELOPMENTAL BIOLOGY (2019)
Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice
Diana Matheoud et al.
NATURE (2019)
mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy
Matteo Bordi et al.
CELL DEATH & DISEASE (2019)
A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy
Qiyao Chai et al.
NATURE COMMUNICATIONS (2019)
Rapamycin for longevity: opinion article
Mikhail V. Blagosklonny
AGING-US (2019)
The ADP/ATP translocase drives mitophagy independent of nucleotide exchange
Atsushi Hoshino et al.
NATURE (2019)
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction
Kurt A. Escobar et al.
AGING CELL (2019)
Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response
James C. Jiang et al.
BIOGERONTOLOGY (2019)
Biological Functions of Autophagy Genes: A Disease Perspective
Beth Levine et al.
CELL (2019)
Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury
Honglu Chao et al.
JOURNAL OF NEUROSCIENCE (2019)
A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy
Tomokazu Murakawa et al.
CELL REPORTS (2019)
Resveratrol improves intestinal barrier function, alleviates mitochondrial dysfunction and induces mitophagy in diquat challenged piglets1
Shuting Cao et al.
FOOD & FUNCTION (2019)
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
Penelope A. Andreux et al.
NATURE METABOLISM (2019)
The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans
Miyuki Sato et al.
NATURE CELL BIOLOGY (2018)
NAD metabolism: Implications in aging and longevity
Keisuke Yaku et al.
AGEING RESEARCH REVIEWS (2018)
Mechanism of parkin activation by PINK1
Christina Gladkova et al.
NATURE (2018)
Spermidine in health and disease
Frank Madeo et al.
SCIENCE (2018)
Resveratrol attenuates oxidative damage through activating mitophagy in an in vitro model of Alzheimer's disease
Hui Wang et al.
TOXICOLOGY LETTERS (2018)
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity
Tingting Fu et al.
CELL REPORTS (2018)
Aspirin Recapitulates Features of Caloric Restriction
Federico Pietrocola et al.
CELL REPORTS (2018)
Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy
Masashi Sugo et al.
EMBO JOURNAL (2018)
Parkin and PINK1 mitigate STING-induced inflammation
Danielle A. Sliter et al.
NATURE (2018)
HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα
Anthea Di Rita et al.
NATURE COMMUNICATIONS (2018)
Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice
Rio Sebori et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Biparental Inheritance of Mitochondrial DNA in Humans
Shiyu Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury
Qiang Li et al.
FRONTIERS IN NEUROSCIENCE (2018)
Mitochondrial fission facilitates the selective mitophagy of protein aggregates
Jonathon L. Burman et al.
JOURNAL OF CELL BIOLOGY (2017)
MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling
Alberto Bartolome et al.
MOLECULAR AND CELLULAR BIOLOGY (2017)
Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway
Francois Le Guerroue et al.
MOLECULAR CELL (2017)
Neutrophil-derived mitochondrial DNA promotes receptor activator of nuclear factor κB and its ligand signalling in rheumatoid arthritis
Anne Contis et al.
RHEUMATOLOGY (2017)
AGING A conserved NAD+ binding pocket that regulates protein-protein interactions during aging
Jun Li et al.
SCIENCE (2017)
Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
W. K. Eddie Ip et al.
SCIENCE (2017)
Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms
Jesse S. Kerr et al.
TRENDS IN NEUROSCIENCES (2017)
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
Rhianna C. Laker et al.
NATURE COMMUNICATIONS (2017)
Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins
Vladimir V. Rogov et al.
SCIENTIFIC REPORTS (2017)
Tomatidine enhances lifespan and healthspan in C-elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Evandro F. Fang et al.
SCIENTIFIC REPORTS (2017)
FKBP8 recruits LC3A to mediate Parkin-independent mitophagy
Zambarlal Bhujabal et al.
EMBO REPORTS (2017)
Mitochondrial E3 ligase MARCH5 regulates FUNDC1 to fine-tune hypoxic mitophagy
Ziheng Chen et al.
EMBO REPORTS (2017)
Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
Yongjie Wei et al.
CELL (2017)
The gut-brain axis: is intestinal inflammation a silent driver of Parkinson's disease pathogenesis?
Madelyn C. Houser et al.
NPJ PARKINSONS DISEASE (2017)
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy
Ming Chen et al.
AUTOPHAGY (2016)
Activation of apoptosis signalling pathways by reactive oxygen species
Maureen Redza-Dutordoir et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML
Mohammed Dany et al.
BLOOD (2016)
Metabolic Control of Longevity
Carlos Lopez-Otin et al.
CELL (2016)
Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation
Diana Matheoud et al.
CELL (2016)
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
Zhenyu Zhong et al.
CELL (2016)
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Evandro Fei Fang et al.
CELL METABOLISM (2016)
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions
Wenxian Wu et al.
EMBO JOURNAL (2016)
The role of Resveratrol-induced mitophagy/autophagy in peritoneal mesothelial cells inflammatory injury via NLRP3 inflammasome activation triggered by mitochondrial ROS
Jun Wu et al.
EXPERIMENTAL CELL RESEARCH (2016)
BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy
Tongmei Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation
Thanh Ngoc Nguyen et al.
JOURNAL OF CELL BIOLOGY (2016)
Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system
Gian-Luca McLelland et al.
JOURNAL OF CELL BIOLOGY (2016)
Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents
Dongryeol Ryu et al.
NATURE MEDICINE (2016)
Cardioprotection and lifespan extension by the natural polyamine spermidine
Tobias Eisenberg et al.
NATURE MEDICINE (2016)
Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization
Qinghua Zhou et al.
SCIENCE (2016)
Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex
Darius Ebrahimi-Fakhari et al.
CELL REPORTS (2016)
Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
Rebecca Rojansky et al.
ELIFE (2016)
The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases
Kiichi Nakahira et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Kinetic and Structural Basis for Acyl-Group Selectivity and NAD+ Dependence in Sirtuin-Catalyzed Deacylation
Jessica L. Feldman et al.
BIOCHEMISTRY (2015)
Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans
Alfonso Schiavi et al.
CURRENT BIOLOGY (2015)
The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway
Feng Gao et al.
HUMAN MOLECULAR GENETICS (2015)
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
Jin-Mi Heo et al.
MOLECULAR CELL (2015)
Autophagy mediates degradation of nuclear lamina
Zhixun Dou et al.
NATURE (2015)
Coordination of mitophagy and mitochondrial biogenesis during ageing in C-elegans
Konstantinos Palikaras et al.
NATURE (2015)
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
Keisuke Mochida et al.
NATURE (2015)
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Michael Lazarou et al.
NATURE (2015)
Mitochondrial DNA stress primes the antiviral innate immune response
A. Phillip West et al.
NATURE (2015)
INFLAMMATION IS GENETICALLY IMPLICATED IN PARKINSON'S DISEASE
N. Dzamko et al.
NEUROSCIENCE (2015)
Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice
Guohua Gong et al.
SCIENCE (2015)
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
Tomokazu Murakawa et al.
NATURE COMMUNICATIONS (2015)
Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice
Jean-Philippe Leduc-Gaudet et al.
ONCOTARGET (2015)
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
Tobias Wauer et al.
EMBO JOURNAL (2015)
Mitophagy Is Required for Acute Cardioprotection by Simvastatin
Allen M. Andres et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
The BCL2L1 and PGAM5 axis defines hypoxia-induced receptor-mediated mitophagy
Hao Wu et al.
AUTOPHAGY (2014)
Effect of resveratrol on mitochondrial function: Implications in parkin-associated familiar Parkinson's disease
Anna Ferretta et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Paternal Mitochondrial Destruction after Fertilization Is Mediated by a Common Endocytic and Autophagic Pathway in Drosophila
Yoav Politi et al.
DEVELOPMENTAL CELL (2014)
Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
Yusuke Kageyama et al.
EMBO JOURNAL (2014)
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
Gian-Luca McLelland et al.
EMBO JOURNAL (2014)
ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
Wenxian Wu et al.
EMBO REPORTS (2014)
GCN5-like Protein 1 (GCN5L1) Controls Mitochondrial Content through Coordinated Regulation of Mitochondrial Biogenesis and Mitophagy
Iain Scott et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Lesley A. Kane et al.
JOURNAL OF CELL BIOLOGY (2014)
ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery
Sebastian Schuck et al.
JOURNAL OF CELL SCIENCE (2014)
A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy
Guo Chen et al.
MOLECULAR CELL (2014)
Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
Guillermo Marino et al.
MOLECULAR CELL (2014)
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
Alban Ordureau et al.
MOLECULAR CELL (2014)
Ubiquitin is phosphorylated by PINK1 to activate parkin
Fumika Koyano et al.
NATURE (2014)
MITOCHONDRIAL REACTIVE OXYGEN SPECIES (ROS) AND ROS-INDUCED ROS RELEASE
Dmitry B. Zorov et al.
PHYSIOLOGICAL REVIEWS (2014)
Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
Yvette C. Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes
Shinya Honda et al.
NATURE COMMUNICATIONS (2014)
Different degree of paternal mtDNA leakage between male and female progeny in interspecific Drosophila crosses
Emmanouil Dokianakis et al.
ECOLOGY AND EVOLUTION (2014)
Proteolytic processing of Atg32 by the mitochondrial i-AAA protease Yme1 regulates mitophagy
Ke Wang et al.
AUTOPHAGY (2013)
PINK1 is degraded through the N-end rule pathway
Koji Yamano et al.
AUTOPHAGY (2013)
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Laurent Mouchiroud et al.
CELL (2013)
Rheb Regulates Mitophagy Induced by Mitochondrial Energetic Status
Su Melser et al.
CELL METABOLISM (2013)
The Scaffold Protein Atg11 Recruits Fission Machinery to Drive Selective Mitochondria Degradation by Autophagy
Kai Mao et al.
DEVELOPMENTAL CELL (2013)
Casein kinase 2 is essential for mitophagy
Tomotake Kanki et al.
EMBO REPORTS (2013)
Loss of iron triggers PINK1/Parkin-independent mitophagy
George F. G. Allen et al.
EMBO REPORTS (2013)
SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage
Anne H. H. Tseng et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation
Shankar S. Iyer et al.
IMMUNITY (2013)
Modulation of Serines 17 and 24 in the LC3-interacting Region of Bnip3 Determines Pro-survival Mitophagy versus Apoptosis
Yanyan Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction
Dieter A. Kubli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Parkin-catalyzed Ubiquitin-Ester Transfer Is Triggered by PINK1-dependent Phosphorylation
Masahiro Iguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Restricted mitochondrial protein acetylation initiates mitochondrial autophagy
Bradley R. Webster et al.
JOURNAL OF CELL SCIENCE (2013)
Extensive paternal mtDNA leakage in natural populations of Drosophila melanogaster
Maria D. S. Nunes et al.
MOLECULAR ECOLOGY (2013)
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
Shireen A. Sarraf et al.
NATURE (2013)
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
Charleen T. Chu et al.
NATURE CELL BIOLOGY (2013)
PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
Yun Chen et al.
SCIENCE (2013)
Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1
Iain Scott et al.
BIOCHEMICAL JOURNAL (2012)
Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition
Mark S. Sharpley et al.
CELL (2012)
A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
Vincent Soubannier et al.
CURRENT BIOLOGY (2012)
Inflammatory cytokines and NT-proCNP in Parkinson's disease patients
Dariusz Koziorowski et al.
CYTOKINE (2012)
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
Andrew W. Greene et al.
EMBO REPORTS (2012)
Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics
Anh H. Pham et al.
GENESIS (2012)
Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition
Robert W. Gilkerson et al.
HUMAN MOLECULAR GENETICS (2012)
Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy
Rita A. Hanna et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
Congcong He et al.
NATURE (2012)
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
Takafumi Oka et al.
NATURE (2012)
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
Lei Liu et al.
NATURE CELL BIOLOGY (2012)
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
R. David Sentelle et al.
NATURE CHEMICAL BIOLOGY (2012)
Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo
Vincent Soubannier et al.
PLOS ONE (2012)
Non-Motor Symptoms in Patients with Parkinson's Disease - Correlations with Inflammatory Cytokines in Serum
Daniel Lindqvist et al.
PLOS ONE (2012)
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
Kahori Shiba-Fukushima et al.
SCIENTIFIC REPORTS (2012)
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
Chandana Kondapalli et al.
OPEN BIOLOGY (2012)
Mitochondria: Sovereign of inflammation?
Juerg Tschopp
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Emma Deas et al.
HUMAN MOLECULAR GENETICS (2011)
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
Nickie C. Chan et al.
HUMAN MOLECULAR GENETICS (2011)
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
Eugenia Morselli et al.
JOURNAL OF CELL BIOLOGY (2011)
Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae
Kai Mao et al.
JOURNAL OF CELL BIOLOGY (2011)
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
Cathrin Meissner et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Phosphorylation of Serine 114 on Atg32 mediates mitophagy
Yoshimasa Aoki et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
Filio Billia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
Daniel F. Egan et al.
SCIENCE (2011)
Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
Philipp Wild et al.
SCIENCE (2011)
Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos
Miyuki Sato et al.
SCIENCE (2011)
Postfertilization Autophagy of Sperm Organelles Prevents Paternal Mitochondrial DNA Transmission
Sara Al Rawi et al.
SCIENCE (2011)
The mitochondrial brain: From mitochondrial genome to neurodegeneration
Helen E. Turnbull et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Nix is a selective autophagy receptor for mitochondrial clearance
Ivana Novak et al.
EMBO REPORTS (2010)
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
Atsushi Tanaka et al.
JOURNAL OF CELL BIOLOGY (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Seok Min Jin et al.
JOURNAL OF CELL BIOLOGY (2010)
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
Der-Fen Suen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Role of Mitochondria in Apoptosis
Chunxin Wang et al.
ANNUAL REVIEW OF GENETICS (2009)
Expression of BNIP3 in invasive breast cancer: correlations with the hypoxic response and clinicopathological features
Esther A. Koop et al.
BMC CANCER (2009)
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
J. Zhang et al.
CELL DEATH AND DIFFERENTIATION (2009)
Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy
Tomotake Kanki et al.
DEVELOPMENTAL CELL (2009)
Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
Koji Okamoto et al.
DEVELOPMENTAL CELL (2009)
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
Hsiuchen Chen et al.
HUMAN MOLECULAR GENETICS (2009)
Mitochondrial Transfer RNAMet 4435A>G Mutation Is Associated With Maternally Inherited Hypertension in a Chinese Pedigree
Yuqi Liu et al.
HYPERTENSION (2009)
Regulation of Autophagy by the p300 Acetyltransferase
In Hye Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
Shankar S. Iyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
Mondira Kundu et al.
BLOOD (2008)
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
Huafeng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration
Tamy C. Frank-Cannon et al.
JOURNAL OF NEUROSCIENCE (2008)
Essential role for Nix in autophagic maturation of erythroid cells
Hector Sandoval et al.
NATURE (2008)
Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFα, and INFγ concentrations are elevated in patients with atypical and idiopathic parkinsonism
Bogdan Brodacki et al.
NEUROSCIENCE LETTERS (2008)
NIX is required for programmed mitochondrial clearance during reticulocyte maturation
Rachel L. Schweers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Selective degradation of mitochondria by mitophagy
Insil Kim et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
A. Hamacher-Brady et al.
CELL DEATH AND DIFFERENTIATION (2007)
Formation of elongated giant mitochondria in DFO-induced cellular senescence: Involvement of enhanced fusion process through modulation of Fis1
Young-Sil Yoon et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
Mitochondrial DNA and ageing
Aleksandra Trifunovic
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)
Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis
N Miyoshi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Mitochondrial DNA deletions serve as biomarkers of aging in the skin, but are typically absent in nonmelanoma skin cancers
Alex Eshaghian et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
Decline in skeletal muscle mitochondrial function with aging in humans
KR Short et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mutations in the mitochondrial DNA D-loop region are frequent in cervical cancer
Himani Sharma et al.
CANCER CELL INTERNATIONAL (2005)
mtDNA mutations increase tumorigenicity in prostate cancer
JA Petros et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Uth1p is involved in the autophagic degradation of mitochondria
I Kissová et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer
J Okami et al.
CANCER RESEARCH (2004)
The pathophysiology of mitochondrial cell death
DR Green et al.
SCIENCE (2004)
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells
S Daido et al.
CANCER RESEARCH (2004)
Premature ageing in mice expressing defective mitochondrial DNA polymerase
A Trifunovic et al.
NATURE (2004)
The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation
W Aerbajinai et al.
BLOOD (2003)
Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts
M Greco et al.
FASEB JOURNAL (2003)
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
KF Petersen et al.
SCIENCE (2003)
Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade
HM Sowter et al.
JOURNAL OF PATHOLOGY (2003)
Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3
LA Kubasiak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Inducible Expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
KM Regula et al.
CIRCULATION RESEARCH (2002)
Ageing muscle:: clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function
G Fayet et al.
NEUROMUSCULAR DISORDERS (2002)
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
G van Loo et al.
CELL DEATH AND DIFFERENTIATION (2002)
Does oxidative damage to DNA increase with age?
ML Hamilton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Endonuclease G is an apoptotic DNase when released from mitochondria
LY Li et al.
NATURE (2001)
Paternal inheritance of mitochondrial DNA in the sheep (Ovine aries)
XB Zhao et al.
SCIENCE IN CHINA SERIES C-LIFE SCIENCES (2001)
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
RK Bruick
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
CY Du et al.
CELL (2000)
The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine heart submitochondrial particles
G Paradies et al.
FEBS LETTERS (2000)