Related references
Note: Only part of the references are listed.Bioinformatics of nanopore sequencing
Wojciech Makalowski et al.
JOURNAL OF HUMAN GENETICS (2020)
Tracking intratumoral heterogeneity in glioblastoma via regularized classification of single-cell RNA-Seq data
Marta B. Lopes et al.
BMC BIOINFORMATICS (2020)
Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent Glioblastoma
Ella L. Kim et al.
CANCERS (2020)
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol
Paul Lesueur et al.
BMC CANCER (2019)
Temozolomide Induced Hypermutation in Glioma: Evolutionary Mechanisms and Therapeutic Opportunities
Paul Daniel et al.
FRONTIERS IN ONCOLOGY (2019)
Atlas of RNA sequencing profiles for normal human tissues
Maria Suntsova et al.
SCIENTIFIC DATA (2019)
Targeting of Histone Demethylases KDM5A and KDM6B Inhibits the Proliferation of Temozolomide-Resistant Glioblastoma Cells
Massimo Romani et al.
CANCERS (2019)
New Paradigm of Machine Learning (ML) in Personalized Oncology: Data Trimming for Squeezing More Biomarkers From Clinical Datasets
Nicolas Borisov et al.
FRONTIERS IN ONCOLOGY (2019)
Do no harm: a roadmap for responsible machine learning for health care
Jenna Wiens et al.
NATURE MEDICINE (2019)
An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis
Po-Hsuan Cameron Chen et al.
NATURE MEDICINE (2019)
Cancer statistics, 2019
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2019)
Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification
Anna Wenger et al.
NEURO-ONCOLOGY (2019)
Prognostic Gene Discovery in Glioblastoma Patients using Deep Learning
Kelvin K. Wong et al.
CANCERS (2019)
A Review on a Deep Learning Perspective in Brain Cancer Classification
Gopal S. Tandel et al.
CANCERS (2019)
Discovering Rare Genes Contributing to Cancer Stemness and Invasive Potential by GBM Single-Cell Transcriptional Analysis
Lin Pang et al.
CANCERS (2019)
Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma
Jaishri O. Blakeley et al.
CLINICAL CANCER RESEARCH (2019)
Assessing Treatment Response of Glioblastoma to an HDAC Inhibitor Using Whole-Brain Spectroscopic MRI
Saumya S. Gurbani et al.
TOMOGRAPHY (2019)
Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas
Katherine B. Peters et al.
JOURNAL OF NEURO-ONCOLOGY (2018)
Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02
Evanthia Galanis et al.
NEURO-ONCOLOGY (2018)
Phase II Study of Bevacizumab and Vorinostat for Patients with Recurrent World Health Organization Grade 4 Malignant Glioma
Ashley Ghiaseddin et al.
ONCOLOGIST (2018)
A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency
Nicolas Borisov et al.
CELL CYCLE (2018)
Information-Based Medicine in Glioma Patients: A Clinical Perspective
Joeky Tamba Senders et al.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2018)
Next-generation sequencing in drug development: target identification and genetically stratified clinical trials
Abolfazl Doostparast Torshizi et al.
DRUG DISCOVERY TODAY (2018)
Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma
Rajendra P. Pangeni et al.
EPIGENETICS (2018)
Current and emerging EGFR therapies for glioblastoma
Stefan Alexandru Artene et al.
JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY (2018)
Tumor treating fields: a new approach to glioblastoma therapy
Jonathan Rick et al.
JOURNAL OF NEURO-ONCOLOGY (2018)
DNA methylation-based classification of central nervous system tumours
David Capper et al.
NATURE (2018)
Nanopore sequencing and assembly of a human genome with ultra-long reads
Miten Jain et al.
NATURE BIOTECHNOLOGY (2018)
Temozolomide-associated hypermutation in gliomas
Serah Choi et al.
NEURO-ONCOLOGY (2018)
Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma
Benjamin M. Ellingson et al.
NEURO-ONCOLOGY (2018)
Using genomics to guide treatment for glioblastoma
Jacob S. Young et al.
PHARMACOGENOMICS (2018)
Chromatin Remodeling Factor BRG1 Regulates Stemness and Chemosensitivity of Glioma Initiating Cells
Debolina Ganguly et al.
STEM CELLS (2018)
Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics
Nathalie E. Synhaeve et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Epigenetic Targeting of Glioblastoma
Massimo Romani et al.
FRONTIERS IN ONCOLOGY (2018)
Curaxin CBL0137 Exerts Anticancer Activity via Diverse Mechanisms
Ming-Zhu Jin et al.
FRONTIERS IN ONCOLOGY (2018)
Late toxicity in long-term survivors from a phase 2 study of concurrent radiation therapy, temozolomide and valproic acid for newly diagnosed glioblastoma
Andra Krauze et al.
NEURO-ONCOLOGY PRACTICE (2018)
PARADIGM-2: Two parallel phase I studies of olaparib and radiotherapy or olaparib and radiotherapy plus temozolomide in patients with newly diagnosed glioblastoma, with treatment stratified by MGMT status
Ben Fulton et al.
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY (2018)
Effect of valproic acid on survival in glioblastoma: A prospective single-arm study
Deepthi Valiyaveettil et al.
SOUTH ASIAN JOURNAL OF CANCER (2018)
Glioblastoma under Siege: An Overview of Current Therapeutic Strategies
Mayra Paolillo et al.
BRAIN SCIENCES (2018)
Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma
Shinichi Watanabe et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2017)
Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide- responsive and - resistant glioblastoma
Tara A. Barone et al.
NEURO-ONCOLOGY (2017)
A novel histone deacetylase inhibitor, CKD5, has potent anti-cancer effects in glioblastoma
Seung Ah Choi et al.
ONCOTARGET (2017)
Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas-robust and informative with caveats
Masoud Movassaghi et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2017)
Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma A Randomized Clinical Trial
Roger Stupp et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)
Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas
Khalil Abou-El-Ardat et al.
NEURO-ONCOLOGY (2017)
The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection
Andrea M. Muscat et al.
Oncotarget (2017)
Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
Spyros Darmanis et al.
CELL REPORTS (2017)
Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma
Maria J. Williams et al.
Frontiers in Oncology (2017)
The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells
Hiroaki Hiramatsu et al.
SCIENTIFIC REPORTS (2017)
Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing
Philipp Euskirchen et al.
ACTA NEUROPATHOLOGICA (2017)
From machine learning to deep learning: progress in machine intelligence for rational drug discovery
Lu Zhang et al.
DRUG DISCOVERY TODAY (2017)
Unsupervised deep learning reveals prognostically relevant subtypes of glioblastoma
Jonathan D. Young et al.
BMC BIOINFORMATICS (2017)
Temozolomide in the Era of Precision Medicine
Anish Thomas et al.
CANCER RESEARCH (2017)
Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification
Lakshminarayan M. Iyer et al.
BIOESSAYS (2016)
A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study
H. Ian Robins et al.
JOURNAL OF NEURO-ONCOLOGY (2016)
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
David N. Louis et al.
ACTA NEUROPATHOLOGICA (2016)
Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models
Josephine Kam Tai Dermawan et al.
CANCER RESEARCH (2016)
Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
Michele Ceccarelli et al.
CELL (2016)
Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma
Caroline Happold et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas
Soeren Mueller et al.
MOLECULAR SYSTEMS BIOLOGY (2016)
DNA methylation on N6-adenine in mammalian embryonic stem cellse
Tao P. Wu et al.
NATURE (2016)
Big data visualization identifies the multidimensional molecular landscape of human gliomas
Hamid Bolouri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma
Nicole R. Parker et al.
SCIENTIFIC REPORTS (2016)
Hallmarks of glioblastoma: a systematic review
Dorte Schou Noroxe et al.
ESMO OPEN (2016)
Long-term survival in glioblastoma: methyl guanine methyl transferase (MGMT) promoter methylation as independent favourable prognostic factor
Uros Smrdel et al.
RADIOLOGY AND ONCOLOGY (2016)
Temozolomide resistance in glioblastoma multiforme
Sang Y. Lee
GENES & DISEASES (2016)
Glioblastoma: pathology, molecular mechanisms and markers
Kenneth Aldape et al.
ACTA NEUROPATHOLOGICA (2015)
Spatiotemporal Evolution of the Primary Glioblastoma Genome
Jinkuk Kim et al.
CANCER CELL (2015)
Machine Learning in Medicine
Rahul C. Deo
CIRCULATION (2015)
Understanding next generation sequencing in oncology: A guide for oncologists
Sing Yu Moorcraft et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2015)
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma
Andra V. Krauze et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2015)
Circulating biomarkers for gliomas
Manfred Westphal et al.
NATURE REVIEWS NEUROLOGY (2015)
Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma
Eudocia Q. Lee et al.
NEURO-ONCOLOGY (2015)
Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone
Jean-Michel Lemee et al.
NEURO-ONCOLOGY (2015)
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
Mona Meyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Glioma
Michael Weller et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
The evolution of nanopore sequencing
Yue Wang et al.
FRONTIERS IN GENETICS (2015)
Haematological toxicity of Valproic acid compared to Levetiracetam in patients with glioblastoma multiforme undergoing concomitant radio-chemotherapy: a retrospective cohort study
Alexander Tinchon et al.
JOURNAL OF NEUROLOGY (2015)
Next generation sequencing technology: Advances and applications
H. P. J. Buermans et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions
Hao Wu et al.
CELL (2014)
Perspectives for immunotherapy in glioblastoma treatment
Gaetano Finocchiaro et al.
CURRENT OPINION IN ONCOLOGY (2014)
A novel approach to the discovery of survival biomarkers in glioblastoma using a joint analysis of DNA methylation and gene expression
Ashley A. Smith et al.
EPIGENETICS (2014)
Using the molecular classification of glioblastoma to inform personalized treatment
Adriana Olar et al.
JOURNAL OF PATHOLOGY (2014)
A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a Pediatric Brain Tumor Consortium report
Jack M. Su et al.
NEURO-ONCOLOGY (2014)
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
Anoop P. Patel et al.
SCIENCE (2014)
Genetics and epigenetics of gliomas
Mario L. Suva
SWISS MEDICAL WEEKLY (2014)
EGFR Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing
Joshua M. Francis et al.
CANCER DISCOVERY (2014)
Current Vaccine Trials in Glioblastoma: A Review
LindaW. Xu et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2014)
H3F3A K27M Mutation in Pediatric CNS Tumors A Marker for Diffuse High-Grade Astrocytomas
Gerrit H. Gielen et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2013)
The Somatic Genomic Landscape of Glioblastoma
Cameron W. Brennan et al.
CELL (2013)
Predictive biomarkers in adult gliomas: the present and the future
Laure Thomas et al.
CURRENT OPINION IN ONCOLOGY (2013)
Identification of prognostic gene signatures of glioblastoma: a study based on TCGA data analysis
Yong-Wan Kim et al.
NEURO-ONCOLOGY (2013)
Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme
Melissa Kerkhof et al.
NEURO-ONCOLOGY (2013)
CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010
Quinn T. Ostrom et al.
NEURO-ONCOLOGY (2013)
DNA Methylation and Its Basic Function
Lisa D. Moore et al.
NEUROPSYCHOPHARMACOLOGY (2013)
Stepping stones in DNA sequencing
Henrik Stranneheim et al.
BIOTECHNOLOGY JOURNAL (2012)
Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03
Eudocia Q. Lee et al.
CLINICAL CANCER RESEARCH (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al.
NATURE (2012)
Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma
Prakash Chinnaiyan et al.
NEURO-ONCOLOGY (2012)
Long-term survival of patients suffering from glioblastoma multiforme treated with tumor-treating fields
Aaron Michael Rulseh et al.
WORLD JOURNAL OF SURGICAL ONCOLOGY (2012)
Regulation of chromatin by histone modifications
Andrew J. Bannister et al.
CELL RESEARCH (2011)
Next-generation sequencing: emerging lessons on the origins of human cancer
Gerd P. Pfeifer et al.
CURRENT OPINION IN ONCOLOGY (2011)
A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03
Fabio M. Iwamoto et al.
NEURO-ONCOLOGY (2011)
High-throughput DNA sequencing - concepts and limitations
Martin Kircher et al.
BIOESSAYS (2010)
DNA methylation in glioblastoma: impact on gene expression and clinical outcome
Amandine Etcheverry et al.
BMC GENOMICS (2010)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak et al.
CANCER CELL (2010)
MicroRNAs and cancer epigenetics: a macrorevolution
Veronica Davalos et al.
CURRENT OPINION IN ONCOLOGY (2010)
Control and reversal of the electrophoretic force on DNA in a charged nanopore
Binquan Luan et al.
JOURNAL OF PHYSICS-CONDENSED MATTER (2010)
APPLICATIONS OF NEXT-GENERATION SEQUENCING Sequencing technologies - the next generation
Michael L. Metzker
NATURE REVIEWS GENETICS (2010)
Base-By-Base Ratcheting of Single Stranded DNA through a Solid-State Nanopore
Binquan Luan et al.
PHYSICAL REVIEW LETTERS (2010)
DNA methylation and the functional organization of the nuclear compartment
Jesus Espadaa et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
Mesenchymal Migration as a Therapeutic Target in Glioblastoma
Jessie Zhong et al.
JOURNAL OF ONCOLOGY (2010)
Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications
Michael T. McCabe et al.
CLINICAL CANCER RESEARCH (2009)
Prognostic Significance of Molecular Markers and Extent of Resection in Primary Glioblastoma Patients
Joerg Felsberg et al.
CLINICAL CANCER RESEARCH (2009)
Glioblastoma multiforme: a review of therapeutic targets
Okezie O. Kanu et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study
Evanthia Galanis et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Epigenetic mechanisms in glioblastoma multiforme
Raman P. Nagarajan et al.
SEMINARS IN CANCER BIOLOGY (2009)
Advantages and limitations of next-generation sequencing technologies: A comparison of electrophoresis and non-electrophoresis methods
Daniel G. Hert et al.
ELECTROPHORESIS (2008)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
The potential and challenges of nanopore sequencing
Daniel Branton et al.
NATURE BIOTECHNOLOGY (2008)
Malignant gliomas in adults
Patrick Y. Wen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution
Monica Uddin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
An integrated genomic analysis of human glioblastoma Multiforme
D. Williams Parsons et al.
SCIENCE (2008)
The role of chromatin during transcription
Bing Li et al.
CELL (2007)
Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation
Benoit Cadieux et al.
CANCER RESEARCH (2006)
N6-methyladenine: the other methylated base of DNA
D Ratel et al.
BIOESSAYS (2006)
DrugBank: a comprehensive resource for in silico drug discovery and exploration
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2006)
Emerging technologies in DNA sequencing
ML Metzker
GENOME RESEARCH (2005)
Histone structure and nucleosome stability
Leonardo Marino-Ramirez et al.
EXPERT REVIEW OF PROTEOMICS (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Finishing the euchromatic sequence of the human genome
FS Collins et al.
NATURE (2004)
Genetic pathways to glioblastoma:: A population-based study
H Ohgaki et al.
CANCER RESEARCH (2004)