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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
Takao Iwawaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A kinase inhibitor activates the IRE1α RNase to confer cytoprotection against ER stress
Han Dan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
IRE1β inhibits chylomicron production by selectively degrading MTP mRNA
Jahangir Iqbal et al.
CELL METABOLISM (2008)
Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects
Sara M. Reyna et al.
DIABETES (2008)
Protein quality control in the early secretory pathway
Tiziana Anelli et al.
EMBO JOURNAL (2008)
Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis
Beixue Gao et al.
EMBO REPORTS (2008)
RNase domains determine the functional difference between IRE1α and IRE1β
Yusuke Imagawa et al.
FEBS LETTERS (2008)
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response
Dianhong Luo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Sweet taste receptor interacting protein CIB1 is a general inhibitor of InsP3-dependent Ca2+ release in vivo
Jan K. Hennings et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress
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MOLECULAR AND CELLULAR BIOLOGY (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
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MOLECULAR CELL (2008)
IRE1β is required for mesoderm formation in Xenopus embryos
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MECHANISMS OF DEVELOPMENT (2008)
Regulation of hepatic lipogenesis by the transcription factor XBP1
Ann-Hwee Lee et al.
SCIENCE (2008)
SOCS proteins causing trouble in insulin action
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ACTA PHYSIOLOGICA (2008)
IRE1 signaling affects cell fate during the unfolded protein response
Jonathan H. Lin et al.
SCIENCE (2007)
Sigma-1 receptor chaperones at the ER-Mitochondrion interface regulate Ca2+ signaling and cell survival
Teruo Hayashi et al.
CELL (2007)
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins
Yukio Kimata et al.
JOURNAL OF CELL BIOLOGY (2007)
The transcription factor XBP-1 is essential for the development and survival of dendritic cells
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JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1
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JOURNAL OF CELL SCIENCE (2007)
The p85α regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance
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MOLECULAR AND CELLULAR BIOLOGY (2007)
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1 (S)-induced endoplasmic reticulum biogenesis
Rungtawan Sriburi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
HCV and CSFVIRES domain II mediate eIF2 release during 80S ribosome assembly
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EMBO JOURNAL (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
PHYSIOLOGICAL REVIEWS (2007)
Attenuation of leptin and insulin signaling by SOCS proteins
Jane K. Howard et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2006)
Dcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiae
Jinbai Guo et al.
EMBO REPORTS (2006)
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
Jiahai Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1
Kathryn L. Lipson et al.
CELL METABOLISM (2006)
Tumour-necrosis-factor-receptor-1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK
Qingfeng Yang et al.
EMBO REPORTS (2006)
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1α
C Hetz et al.
SCIENCE (2006)
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression
P Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
KZ Zhang et al.
CELL (2006)
Yeast unfolded protein response pathway regulates expression of genes for anti-oxidative stress and for cell surface proteins
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GENES TO CELLS (2006)
The endoplasmic reticulum: Folding, calcium homeostasis, signaling, and redox control
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ANTIOXIDANTS & REDOX SIGNALING (2006)
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
AH Lee et al.
EMBO JOURNAL (2005)
An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1
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BIOCHEMICAL JOURNAL (2005)
Overexpression of cyclin D1 in pancreatic β-cells in vivo results in islet hyperplasia without hypoglycemia
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DIABETES (2005)
Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis
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EMBO JOURNAL (2004)
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress
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MOLECULAR BIOLOGY OF THE CELL (2004)
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
[Anonymous]
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire 1
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JOURNAL OF CELL BIOLOGY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
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SCIENCE (2004)
JAB1 participates in unfolded protein responses by association and dissociation with IRE1
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NEUROCHEMISTRY INTERNATIONAL (2004)
Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins
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MOLECULAR BIOLOGY OF THE CELL (2003)
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1α
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MOLECULAR AND CELLULAR BIOLOGY (2002)
A central role for JNK in obesity and insulin resistance
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NATURE (2002)
The protein kinase/endoribonuclease IRE1α that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain
CY Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
IREI-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
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GENES & DEVELOPMENT (2002)
Calcium signaling: A tale for all seasons
E Carafoli
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
M Calfon et al.
NATURE (2002)
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
H Yoshida et al.
CELL (2001)
Plasma cell differentiation requires the transcription factor XBP-1
AM Reimold et al.
NATURE (2001)
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress
T Iwawaki et al.
NATURE CELL BIOLOGY (2001)
Sarco(endo)plasmic reticulum calcium pumps: recent advances in our understanding of structure/function and biology (Review)
JM East
MOLECULAR MEMBRANE BIOLOGY (2000)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
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NATURE CELL BIOLOGY (2000)
MRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
C Tournier et al.
SCIENCE (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
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NATURE (2000)
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