Related references
Note: Only part of the references are listed.Application of an in Vitro Blood-Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington's Disease
Annalise Di Marco et al.
MOLECULAR PHARMACEUTICS (2019)
Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs
Yuan Li et al.
NEUROSCIENCE BULLETIN (2019)
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
Tae-Eun Park et al.
NATURE COMMUNICATIONS (2019)
The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model
Moriah E. Katt et al.
FLUIDS AND BARRIERS OF THE CNS (2019)
Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model
Gwenaelle Le Roux et al.
SCIENTIFIC REPORTS (2019)
Tissue-engineered blood-brain barrier models via directed differentiation of human induced pluripotent stem cells
Gabrielle N. Grifno et al.
SCIENTIFIC REPORTS (2019)
Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides
Alberto Bresciani et al.
ACS MEDICINAL CHEMISTRY LETTERS (2019)
The Role of VE-cadherin in Blood-brain Barrier Integrity under Central Nervous System Pathological Conditions
Wenlu Li et al.
CURRENT NEUROPHARMACOLOGY (2018)
A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis
Maria Ribecco-Lutkiewicz et al.
SCIENTIFIC REPORTS (2018)
Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development
Samuel Sances et al.
STEM CELL REPORTS (2018)
Barrier Properties and Transcriptome Expression in Human iPSC-Derived Models of the Blood-Brain Barrier
Louise Delsing et al.
STEM CELLS (2018)
Expression and Functional Characterization of Drug Transporters in Brain Microvascular Endothelial Cells Derived from Human Induced Pluripotent Stem Cells
Toshiki Kurosawa et al.
MOLECULAR PHARMACEUTICS (2018)
Transport of Pregabalin Via L-Type Amino Acid Transporter 1 (SLC7A5) in Human Brain Capillary Endothelial Cell Line
Yu Takahashi et al.
PHARMACEUTICAL RESEARCH (2018)
Benchmarking in vitro tissue-engineered blood-brain barrier models
Jackson G. DeStefano et al.
FLUIDS AND BARRIERS OF THE CNS (2018)
A perfused human blood-brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport
Nienke R. Wevers et al.
FLUIDS AND BARRIERS OF THE CNS (2018)
Altered GABAA receptor density and unaltered blood-brain barrier [11C]flumazenil transport in drug-resistant epilepsy patients with mesial temporal sclerosis
Femke E. Froklage et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2017)
Huntington's Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits
Ryan G. Lim et al.
CELL REPORTS (2017)
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells
Antje Appelt-Menzel et al.
STEM CELL REPORTS (2017)
Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells
Abraham J. Al-Ahmad
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2017)
Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier
Gad D. Vatine et al.
CELL STEM CELL (2017)
On the Dependency of Cellular Protein Levels on mRNA Abundance
Yansheng Liu et al.
CELL (2016)
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
Hans C. Helms et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2016)
Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells
Matthew J. Stebbins et al.
METHODS (2016)
Minimum Transendothelial Electrical Resistance Thresholds for the Study of Small and Large Molecule Drug Transport in a Human in Vitro Blood-Brain Barrier Model
Jennifer L. Mantle et al.
MOLECULAR PHARMACEUTICS (2016)
Cryopreservation of Brain Endothelial Cells Derived from Human Induced Pluripotent Stem Cells Is Enhanced by Rho-Associated Coiled Coil-Containing Kinase Inhibition
Hannah K. Wilson et al.
TISSUE ENGINEERING PART C-METHODS (2016)
Stem Cell-Based Human Blood-Brain Barrier Models for Drug Discovery and Delivery
S. Aday et al.
TRENDS IN BIOTECHNOLOGY (2016)
Human Brain Microvascular Endothelial Cells Derived from the BC1 iPS Cell Line Exhibit a Blood-Brain Barrier Phenotype
Moriah E. Katt et al.
PLOS ONE (2016)
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons
J. Lenzi et al.
Disease Models & Mechanisms (2015)
Blood-brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery
William M. Pardridge
EXPERT OPINION ON THERAPEUTIC TARGETS (2015)
Development of a Series of Aryl Pyrimidine Kynurenine Monooxygenase Inhibitors as Potential Therapeutic Agents for the Treatment of Huntington's Disease
Leticia M. Toledo-Sherman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Blood-brain barrier models: in vitro to in vivo translation in preclinical development of CNS-targeting biotherapeutics
Danica B. Stanimirovic et al.
EXPERT OPINION ON DRUG DISCOVERY (2015)
A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes
Louiza Bohn Thomsen et al.
PLOS ONE (2015)
Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells
Hannah K. Wilson et al.
FLUIDS AND BARRIERS OF THE CNS (2015)
A Human Blood-Brain Barrier Transcytosis Assay Reveals Antibody Transcytosis Influenced by pH-Dependent Receptor Binding
Hadassah Sade et al.
PLOS ONE (2014)
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
Ethan S. Lippmann et al.
SCIENTIFIC REPORTS (2014)
Hurdles with Using In Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: A Special Focus on Transporters and Metabolizing Enzymes
Ramzi Shawahna et al.
CURRENT DRUG METABOLISM (2013)
Blood-brain barrier structure and function and the challenges for CNS drug delivery
N. Joan Abbott
JOURNAL OF INHERITED METABOLIC DISEASE (2013)
Characterization and Modulation of Glucose Uptake in a Human Blood-Brain Barrier Model
Manuela Meireles et al.
JOURNAL OF MEMBRANE BIOLOGY (2013)
Brain Efflux Index To Investigate the Influence of Active Efflux on Brain Distribution of Pemetrexed and Methotrexate
Li Li et al.
DRUG METABOLISM AND DISPOSITION (2013)
The Role of Glucose Transporters in Brain Disease: Diabetes and Alzheimer's Disease
Kaushik Shah et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
Ethan S. Lippmann et al.
NATURE BIOTECHNOLOGY (2012)
Transport of Selected PET Radiotracers by Human P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2): An In Vitro Screening
Nicolas Tournier et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
Spatial and temporal expression pattern of germ layer markers during human embryonic stem cell differentiation in embryoid bodies
Mari Pekkanen-Mattila et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2010)
The Protein Family of Glucose Transport Facilitators: It's Not Only About Glucose After All
Robert Augustin
IUBMB LIFE (2010)
Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human
Mark S. Warren et al.
PHARMACOLOGICAL RESEARCH (2009)
VE-cadherin - The major endothelial adhesion molecule controlling cellular junctions and blood vessel formation
Dietmar Vestweber
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)
Induced pluripotent stem cell lines derived from human somatic cells
Junying Yu et al.
SCIENCE (2007)
Feeder-independent culture of human embryonic stem cells
Tenneille E. Ludwig et al.
NATURE METHODS (2006)
A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene
AM Dumitrescu et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier
T Eisenblätter et al.
BRAIN RESEARCH (2003)
Share Paper
