4.6 Review

Green Chemistry Synthesis of Silver Nanoparticles and Their Potential Anticancer Effects

Journal

CANCERS
Volume 12, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/cancers12040855

Keywords

silver nanoparticles; green chemistry; cancer; anti-cancer effect

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Funding

  1. National Research Foundation of Korea (NRF) - Ministry of Education, Korea [2017R1A6A1A03015642]

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Nanobiotechnology has grown rapidly and become an integral part of modern disease diagnosis and treatment. Biosynthesized silver nanoparticles (AgNPs) are a class of eco-friendly, cost-effective and biocompatible agents that have attracted attention for their possible biomedical and bioengineering applications. Like many other inorganic and organic nanoparticles, such as AuNPs, iron oxide and quantum dots, AgNPs have also been widely studied as components of advanced anticancer agents in order to better manage cancer in the clinic. AgNPs are typically produced by the action of reducing reagents on silver ions. In addition to numerous laboratory-based methods for reduction of silver ions, living organisms and natural products can be effective and superior source for synthesis of AgNPs precursors. Currently, plants, bacteria and fungi can afford biogenic AgNPs precursors with diverse geometries and surface properties. In this review, we summarized the recent progress and achievements in biogenic AgNPs synthesis and their potential uses as anticancer agents.

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