4.5 Editorial Material

Moving from probiotics to precision probiotics

Journal

NATURE MICROBIOLOGY
Volume 5, Issue 7, Pages 878-880

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41564-020-0721-1

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Funding

  1. Abisch Frenkel Foundation for the Promotion of Life Sciences
  2. Gurwin Family Fund for Scientific Research
  3. Leona M. and Harry B. Helmsley Charitable Trust
  4. Crown Endowment Fund for Immunological Research
  5. Else Kroener Fresenius Foundation
  6. Benoziyo Endowment Fund for the Advancement of Science
  7. Adelis Foundation
  8. French National Center for Scientific Research (CNRS)
  9. Israel Science Foundation
  10. Helmholtz Foundation
  11. European Research Council
  12. estate of J. Gitlitz
  13. estate of L. Hershkovich

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A precision approach to probiotics could address the heterogeneity inherent to probiotic strains, the hosts and their microbiomes. Here, we discuss the steps required to develop precision probiotics: mechanistic studies, phenotypic and target-based discovery strategies, and person-centric trials.

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