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Phase I dose-escalation study of the protein kinase C (PKC) inhibitor AEB071 in patients with metastatic uveal melanoma.
Sophie Piperno-Neumann et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Disseminated tumour cells in bone marrow of patients with uveal melanoma
Nils Eide et al.
ACTA OPHTHALMOLOGICA (2013)
Patient-Derived Tumor Xenografts: Transforming Clinical Samples into Mouse Models
Despina Siolas et al.
CANCER RESEARCH (2013)
Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
Marcel Martin et al.
NATURE GENETICS (2013)
Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
J. William Harbour et al.
NATURE GENETICS (2013)
Gene Expressing Profiling of Iris Melanomas
J. William Harbour et al.
OPHTHALMOLOGY (2013)
Iris Nevus Growth into Melanoma: Analysis of 1611 Consecutive Eyes The ABCDEF Guide
Carol L. Shields et al.
OPHTHALMOLOGY (2013)
Iris Melanoma Management with Iodine-125 Plaque Radiotherapy in 144 Patients: Impact of Melanoma-Related Glaucoma on Outcomes
Carol L. Shields et al.
OPHTHALMOLOGY (2013)
Prevalence of germline BAP1 mutation in a population-based sample of uveal melanoma cases
Lauren G. Aoude et al.
PIGMENT CELL & MELANOMA RESEARCH (2013)
Hepatic Stellate Cells Secreted Hepatocyte Growth Factor Contributes to the Chemoresistance of Hepatocellular Carcinoma
Guofeng Yu et al.
PLOS ONE (2013)
CHOROIDAL MELANOMA Does Endoresection Prevent Neovascular Glaucoma in Patient Treated with Proton Beam Irradiation?
Nathalie Cassoux et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2013)
SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Simon J. Furney et al.
CANCER DISCOVERY (2013)
Progression of Ocular Melanoma Metastasis to the Liver
Hans E. Grossniklaus
JAMA OPHTHALMOLOGY (2013)
A nurse-led ocular oncology clinic in Liverpool: results of a 6-month trial
T. Sandinha et al.
EYE (2012)
Progress in the management of patients with uveal melanoma. The 2012 Ashton Lecture
B. Damato
EYE (2012)
Iris melanoma: Features and prognosis in 317 children and adults
Carol L. Shields et al.
JOURNAL OF AAPOS (2012)
Detection and Time to Treatment of Uveal Melanoma in the United Kingdom: An Evaluation of 2384 Patients
Erika M. Damato et al.
OPHTHALMOLOGY (2012)
Collaborative Ocular Oncology Group Report Number 1: Prospective Validation of a Multi-Gene Prognostic Assay in Uveal Melanoma
Michael D. Onken et al.
OPHTHALMOLOGY (2012)
Clinical Survey of 3680 Iris Tumors Based on Patient Age at Presentation
Carol L. Shields et al.
OPHTHALMOLOGY (2012)
Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus in 104 Cases
Sanket U. Shah et al.
OPHTHALMOLOGY (2012)
The Classical Pink-Eyed Dilution Mutation Affects Angiogenic Responsiveness
Michael S. Rogers et al.
PLOS ONE (2012)
Phase II Trial of Sorafenib in Combination with Carboplatin and Paclitaxel in Patients with Metastatic Uveal Melanoma: SWOG S0512
Shailender Bhatia et al.
PLOS ONE (2012)
SECTOR LASER PHOTOCOAGULATION FOR THE PREVENTION OF MACULAR EDEMA AFTER PLAQUE RADIOTHERAPY FOR UVEAL MELANOMA A Pilot Study
Miguel A. Materin et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2012)
CLINICAL SPECTRUM AND PROGNOSIS OF UVEAL MELANOMA BASED ON AGE AT PRESENTATION IN 8,033 CASES
Carol L. Shields et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2012)
Intravital Microscopy Through an Abdominal Imaging Window Reveals a Pre-Micrometastasis Stage During Liver Metastasis
Laila Ritsma et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Histopathological Growth Pattern, Proteolysis and Angiogenesis in Chemonaive Patients Resected forMultiple Colorectal LiverMetastases
Rikke Lovendahl Eefsen et al.
JOURNAL OF ONCOLOGY (2012)
Different Subsets of Tumor-Infiltrating Lymphocytes Correlate with Macrophage Influx and Monosomy 3 in Uveal Melanoma
Inge H. G. Bronkhorst et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)
Modeling Human Choroidal Melanoma Xenograft Growth in Immunocompromised Rodents to Assess Treatment Efficacy
Rod D. Braun et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)
Enhancing survival prognostication in patients with choroidal melanoma by integrating pathologic, clinical and genetic predictors of metastasis
Antonio Eleuteri et al.
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING AND TECHNOLOGY (2012)
Adjuvant intravenous therapy by fotemustine in uveal melanoma : a randomised study
L DESJARDINS et al.
ACTA OPHTHALMOLOGICA (2011)
Anterior Segment Tumor Biopsy Using an Aspiration Cutter Technique: Clinical Experience
Vasileios Petousis et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2011)
Uveal Melanoma and BRCA1/BRCA2 Genes: A Relationship That Needs Further Investigation
Cristina Cruz et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Germline mutations in BAP1 predispose to melanocytic tumors
Thomas Wiesner et al.
NATURE GENETICS (2011)
Choroidal Melanoma and Lid Fibrofoliculomas in Birt-Hogg-Dube Syndrome
Irene Canal Fontcuberta et al.
OPHTHALMIC GENETICS (2011)
Plaque Radiotherapy for Juxtapapillary Choroidal Melanoma Tumor Control in 650 Consecutive Cases
Mandeep S. Sagoo et al.
OPHTHALMOLOGY (2011)
Prognosis of Uveal Melanoma in 500 Cases Using Genetic Testing of Fine-Needle Aspiration Biopsy Specimens
Carol L. Shields et al.
OPHTHALMOLOGY (2011)
Uveal Melanoma: Trends in Incidence, Treatment, and Survival
Arun D. Singh et al.
OPHTHALMOLOGY (2011)
The mouse pink-eyed dilution allele of the P-gene greatly inhibits eumelanin but not pheomelanin synthesis
Tomohisa Hirobe et al.
PIGMENT CELL & MELANOMA RESEARCH (2011)
Estimating prognosis for survival after treatment of choroidal melanoma
Bertil Damato et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2011)
TREATMENT OF AMELANOTIC CHOROIDAL MELANOMA WITH PHOTODYNAMIC THERAPY
William G. Campbell et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2011)
Detection of M2-Macrophages in Uveal Melanoma and Relation with Survival
Inge H. G. Bronkhorst et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Fourier domain optical coherence tomographic and auto-fluorescence findings in indeterminate choroidal melanocytic lesions
Arun D. Singh et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2010)
Cancer family history characterization in an unselected cohort of 121 patients with uveal melanoma
M. H. Abdel-Rahman et al.
FAMILIAL CANCER (2010)
Dipyrimidine Amines: A Novel Class of Chemokine Receptor. Type 4 Antagonists with High Specificity
Aizhi Zhu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers
Laura Baglietto et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
Johanna C. Scheuermann et al.
NATURE (2010)
Phase 2 open-label study of weekly docosahexaenoic acid-paclitaxel in patients with metastatic uveal melanoma
Jade Homsi et al.
MELANOMA RESEARCH (2010)
Mutations in GNA11 in Uveal Melanoma.
Catherine D. Van Raamsdonk et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
J. William Harbour et al.
SCIENCE (2010)
Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients
Nils Eide et al.
ACTA OPHTHALMOLOGICA (2009)
MALIGNANT MELANOMAS OF THE HUMAN UVEA
O. A. JENSEN
ACTA OPHTHALMOLOGICA (2009)
Metastasis of Uveal Melanoma Millimeter-by-Millimeter in 8033 Consecutive Eyes
Carol L. Shields et al.
ARCHIVES OF OPHTHALMOLOGY (2009)
The epidemiological challenge of the most frequent eye cancer: retinoblastoma, an issue of birth and death
Tero Kivela
BRITISH JOURNAL OF OPHTHALMOLOGY (2009)
Mobile Phone Use and Risk of Uveal Melanoma: Results of the Risk Factors for Uveal Melanoma Case-Control Study
Andreas Stang et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
Catherine D. Van Raamsdonk et al.
NATURE (2009)
Positive Interaction Between Light Iris Color and Ultraviolet Radiation in Relation to the Risk of Uveal Melanoma A Case-Control Study
Andrea Schmidt-Pokrzywniak et al.
OPHTHALMOLOGY (2009)
Periocular Triamcionolone for Prevention of Macular Edema after Plaque Radiotherapy of Uveal Melanoma A Randomized Controlled Trial
Noel Horgan et al.
OPHTHALMOLOGY (2009)
Adjuvant Interferon Therapy for Patients with Uveal Melanoma at High Risk of Metastasis
Anne Marie Lane et al.
OPHTHALMOLOGY (2009)
Immune escape mechanisms of intraocular tumors
Jerry Y. Niederkorn
PROGRESS IN RETINAL AND EYE RESEARCH (2009)
PD-L1 Expression on Human Ocular Cells and Its Possible Role in Regulating Immune-Mediated Ocular Inflammation
Wanhua Yang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Inhibition of Chemokine Receptor Expression on Uveal Melanomas by CXCR4 siRNA and Its Effect on Uveal Melanoma Liver Metastases
Haochuan Li et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Activated CD11b+ CD15+ Granulocytes Increase in the Blood of Patients with Uveal Melanoma
Kyle C. McKenna et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Autofluorescence of choroidal melanoma in 51 cases
C. L. Shields et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2008)
Examination of signalling pathways involved in muscarinic responses in bovine ciliary muscle using YM-254890, an inhibitor of the G(q/11) protein
F. Yasui et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Modulation of the tumor cell phenotype by IFN-γ results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes
Kristian Hallermalm et al.
JOURNAL OF IMMUNOLOGY (2008)
Autofluorescence of choroidal nevus in 64 cases
Carol L. Shields et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2008)
Periocular triamcinolone for prevention of macular edema after iodine 125 plaque radiotherapy of uveal melanoma
Noel Horgan et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2008)
Characterization of melanin in human iridal and choroidal melanocytes from eyes with various colored irides
Kazumasa Wakamatsu et al.
PIGMENT CELL & MELANOMA RESEARCH (2008)
Monosomy of chromosome 3 and an inflammatory phenotype occur together in uveal melanoma
Willem Maat et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Differential expression of chemokine receptors on uveal melanoma cells and their metastases
Haochuan Li et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Incidence of uveal melanoma in Europe
Gianni Virgili et al.
OPHTHALMOLOGY (2007)
Uveal melanoma expression of indoleamine 2,3-deoxygenase: Establishment of an immune privileged environment by tryptophan depletion
Peter W. Chen et al.
EXPERIMENTAL EYE RESEARCH (2007)
Cytogenetics of uveal melanoma - A 7-year clinical experience
Bertil Damato et al.
OPHTHALMOLOGY (2007)
Modeling the behavior of uveal melanoma in the liver
Robert Folberg et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
MHC class II-transduced tumor cells originating in the immune-privileged eye prime and boost CD4+ T lymphocytes that cross-react with primary and metastatic weal melanoma cells
Jacobus J. Bosch et al.
CANCER RESEARCH (2007)
Associations between ocular melanoma and other primary cancers: An international population-based study
Ghislaine Scelo et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
High levels of melanin-related metabolites in plasma from pink-eyed dilution mice
Kazumasa Wakamatsu et al.
PIGMENT CELL RESEARCH (2007)
Proton beam irradiation of uveal melanomas: The first 30 years - The Weisenfeld Lecture
Evangelos S. Gragoudas
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
A prospective single arm phase II study of dacarbazine and treosulfan as first-line therapy in metastatic uveal melanoma
Penny A. O'Neill et al.
MELANOMA RESEARCH (2006)
In vivo detection of monosomy 3 in eyes with medium-sized uveal melanoma using transscleral fine needle aspiration biopsy
E. Midena et al.
EUROPEAN JOURNAL OF OPHTHALMOLOGY (2006)
Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: Effects of altering intracellular pH and pink-eyed dilution gene expression
L Ni-Komatsu et al.
EXPERIMENTAL EYE RESEARCH (2006)
The association between host susceptibility factors and uveal melanoma - A meta-analysis
E Weis et al.
ARCHIVES OF OPHTHALMOLOGY (2006)
Uveal melanoma: A study on incidence of additional cancers in the Swedish population
L Bergman et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
Safety and efficacy of interferon alfa-2b in the adjuvant treatment of uveal melanoma
E. Richtig et al.
OPHTHALMOLOGE (2006)
Estimating the risk of malignant transformation of a choroidal nevus
AD Singh et al.
OPHTHALMOLOGY (2005)
A two-cohort phase II clinical trial of gemcitabine plus treosulfan in patients with metastatic uveal melanoma
A Schmittel et al.
MELANOMA RESEARCH (2005)
Proton beam radiotherapy of iris melanoma
B Damato et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Phase II trial of cisplatin, gemcitabine and treosulfan in patients with metastatic uveal melanoma
A Schmittel et al.
MELANOMA RESEARCH (2005)
Of mice and men: values and liabilities of the athymic nude mouse model in anticancer drug development
LR Kelland
EUROPEAN JOURNAL OF CANCER (2004)
A phase II study of bendamustine chemotherapy as second-line treatment in metastatic uveal melanoma
M Schmidt-Hieber et al.
MELANOMA RESEARCH (2004)
The Zimmerman-McLean-Foster hypothesis: 25 years later
AD Singh et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2004)
Sunlight exposure and pathogenesis of uveal melanoma
AD Singh et al.
SURVEY OF OPHTHALMOLOGY (2004)
The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre-enucleation radiation of large choroidal melanoma: IV. Ten-year mortality findings and prognostic factors. COMS report number 24
BS Hawkins
AMERICAN JOURNAL OF OPHTHALMOLOGY (2004)
High-resolution ultrasonic imaging of the posterior segment
DJ Coleman et al.
OPHTHALMOLOGY (2004)
Secondary retinal changes associated with choroidal naevi and melanomas documented by optical coherence tomography
S Muscat et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2004)
Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
MD Onken et al.
CANCER RESEARCH (2004)
Ocular melanoma: Epidemiology, clinical presentation and relationship with dysplastic nevi
E Richtig et al.
OPHTHALMOLOGICA (2004)
Phase II evaluation of temozolomide in metastatic choroidal melanoma
AY Bedikian et al.
MELANOMA RESEARCH (2003)
Incidence of ocular melanoma in Australia from 1990 to 1998
CM Vajdic et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Ultrasound biomicroscopy in management of malignant iris melanoma
JR Nordlund et al.
ARCHIVES OF OPHTHALMOLOGY (2003)
Bleomycin, vincristine, lomustine and dacarbazine (BOLD) in combination with recombinant interferon alpha-2b for metastatic uveal melanoma
T Kivelä et al.
EUROPEAN JOURNAL OF CANCER (2003)
Expression of classic and nonclassic HLA class I antigens in uveal melanoma
G Anastassiou et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Apoptotic cell death in conjunction with CD80 costimulation confers uveal melanoma cells with the ability to induce immune responses
J Carlring et al.
IMMUNOLOGY (2003)
Expression of the c-kit receptor in choroidal melanomas
F Mouriaux et al.
MELANOMA RESEARCH (2003)
Monosomy 3 in uveal melanoma: Correlation with clinical and histologic predictors of survival
AGM Scholes et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Very long-term prognosis of patients with malignant uveal melanoma
E Kujala et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
How light reaches the eye and its components
DH Sliney
INTERNATIONAL JOURNAL OF TOXICOLOGY (2002)
HLA class I antigen expression correlates with histologic cell type in uveal melanomas
S Dithmar et al.
OPHTHALMOLOGE (2002)
The etiology of oculocutaneous albinism (OCA) type II: The pink protein modulates the processing and transport of tyrosinase
K Toyofuku et al.
PIGMENT CELL RESEARCH (2002)
HLA expression in uveal melanoma: There is no rule without some exception
MJ Jager et al.
HUMAN IMMUNOLOGY (2002)
Primary transpupillary thermotherapy for small choroidal melanoma in 256 consecutive cases - Outcomes and limitations
CL Shields et al.
OPHTHALMOLOGY (2002)
Prevalence of the BRCA2 6174 del T mutation in Israeli uveal melanoma patients
J Iscovich et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Association of ocular melanoma with breast cancer but not with cutaneous melanoma: Results from the Swedish family-cancer database
K Hemminki et al.
INTERNATIONAL JOURNAL OF CANCER (2001)
Microphthalmia transcription factor immunohistochemistry: A useful diagnostic marker in the diagnosis and detection of cutaneous melanoma, sentinel lymph node metastases, and extracutaneous melanocytic neoplasms
FM O'Reilly et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2001)
Plaque radiotherapy for management of ciliary body and choroidal melanoma with extraocular extension
K Gündüz et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2000)