4.6 Review

Comprehensive History of CSP Genes: Evolution, Phylogenetic Distribution and Functions

Journal

GENES
Volume 11, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/genes11040413

Keywords

tandem duplication; RNA mutation; adaptive process; lipid transport; xenobiotic resistance; neuroplasticity

Funding

  1. Natural Sciences Foundation of Shandong Province
  2. Overseas Talent, Taishan Scholar, Agricultural Scientific and Technological Innovation Project of SAAS
  3. Key Research and Development Program of Shandong Province [ZR2011CM046, tshw20091015, CXGC2016A11, 2019GSF107085]

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In this review we present the developmental, histological, evolutionary and functional properties of insect chemosensory proteins (CSPs) in insect species. CSPs are small globular proteins folded like a prism and notoriously known for their complex and arguably obscure function(s), particularly in pheromone olfaction. Here, we focus on direct functional consequences on protein function depending on duplication, expression and RNA editing. The result of our analysis is important for understanding the significance of RNA-editing on functionality of CSP genes, particularly in the brain tissue.

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