4.2 Article

Intelligent Diagnosis of Heart Murmurs in Children with Congenital Heart Disease

Journal

JOURNAL OF HEALTHCARE ENGINEERING
Volume 2020, Issue -, Pages -

Publisher

HINDAWI LTD
DOI: 10.1155/2020/9640821

Keywords

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Funding

  1. Edwards Life-sciences Foundation (One Edwards Way, Irvine, CA, California, United States)
  2. Angel Heart Foundation (Lanzhou, Gansu Province, China), Health Industry Research Project of Gansu Province [GSWSKY2016-04]
  3. National Natural Science Foundation of China [51805218]
  4. Jiangsu Natural Science Foundation [BK20170552]

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Heart auscultation is a convenient tool for early diagnosis of heart diseases and is being developed to be an intelligent tool used in online medicine. Currently, there are few studies on intelligent diagnosis of pediatric murmurs due to congenital heart disease (CHD). The purpose of the study was to develop a method of intelligent diagnosis of pediatric CHD murmurs. Phonocardiogram (PCG) signals of 86 children were recorded with 24 children having normal heart sounds and 62 children having CHD murmurs. A segmentation method based on the discrete wavelet transform combined with Hadamard product was implemented to locate the first and the second heart sounds from the PCG signal. Ten features specific to CHD murmurs were extracted as the input of classifier after segmentation. Eighty-six artificial neural network classifiers were composed into a classification system to identify CHD murmurs. The accuracy, sensitivity, and specificity of diagnosis for heart murmurs were 93%, 93.5%, and 91.7%, respectively. In conclusion, a method of intelligent diagnosis of pediatric CHD murmurs is developed successfully and can be used for online screening of CHD in children.

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