4.3 Article

Equine Influenza

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COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/cshperspect.a038331

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  1. Kentucky Agricultural Experiment Station [KY014053]

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This article introduces the upper respiratory diseases in horses caused by influenza A virus, discussing the genetic evolution and potential for interspecies transmission of equine influenza viruses, as well as their clinical features and epidemiology. Vaccination is considered crucial for controlling equine influenza.
Horses are the third major mammalian species, along with humans and swine, long known to be subject to acute upper respiratory disease from influenza A virus infection. The viruses responsible are subtype H7N7, which is believed extinct, and H3N8, which circulates worldwide. The equine influenza lineages are clearly divergent from avian influenza lineages of the same subtypes. Their genetic evolution and potential for interspecies transmission, as well as clinical features and epidemiology, are discussed. Equine influenza is spread internationally and vaccination is central to control efforts. The current mechanism of international surveillance and virus strain recommendations for vaccines is described.

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