Association between Serum Lipid Levels in Greek Children with Dyslipidemia and Mediterranean Diet Adherence, Dietary Habits, Lifestyle and Family Socioeconomic Factors

Background: Childhood dyslipidemia is an important risk factor for developing cardiovascular disease in adulthood. Our study aimed to investigate a possible correlation between nutritional, lifestyle, behavioral and socioeconomic factors and serum lipid levels in children with dyslipidemia.Methods: In this retrospective, observational study, in 31 children with dyslipidemia, aged 3-14 years, dietary habits, physical activity, hours watching television or playing video games, family's socioeconomic status, weight of children and parents, and duration of breastfeeding were recorded. The children's adherence to the Mediterranean diet was also evaluated by KidMed index. Statistical analysis was performed using SPSS.22.Results: Children with increased physical activity had lower triglyceride levels, compared to those with lower physical activity (p= 0.001). Children who consumed only one meal per day, had increased levels of total cholesterol (p= 0.01), LDL-cholesterol (p= 0.01), ApoB (p= 0.001) and lipoprotein (a) (p= 0.018), compared to those who consumed more than 3 meals per day (p< 0.05). Children who were breastfed less than 6 months had significantly increased LDL-C levels (p= 0.022), compared to children who were breastfed more than 6 months. All other parameters investigated did not differ significantly.Conclusions: This study showed association between lipid profile of children with dyslipidemia and specific nutritional and socioeconomic factors, such as increased physical activity, increased meals consumption during the day, and exclusive breastfeeding for more than 6 months. Nevertheless, further research is needed, in order to confirm these findings.