4.6 Review

Recent Advances in the Synthesis of Indanes and Indenes

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 22, Issue 15, Pages 5056-5094

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201503933

Keywords

carbocyclization; indanes; indenes; reaction mechanisms; synthetic methods

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Indanes and indenes are among the most important carbocycles. Many indane and indene derivatives have shown important pharmacological activities, and the indane and indene nuclei are structural motifs present in several natural products of biological relevance. In spite of their importance, only a few reviews on their preparation methods have appeared so far in the literature, the most recent ones being published about ten years ago. The present Review is aimed at filling this gap, presenting some of the most important and innovative approaches to indanes and indenes that have been published in the course of the last ten years (coverage: from 2005 to May, 2015).

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