Related references
Note: Only part of the references are listed.Upf proteins: highly conserved factors involved in nonsense mRNA mediated decay
Puneet Gupta et al.
MOLECULAR BIOLOGY REPORTS (2018)
Advances in therapeutic use of a drug-stimulated translational readthrough of premature termination codons
Maciej Dabrowski et al.
MOLECULAR MEDICINE (2018)
Deciphering the reading of the genetic code by near-cognate tRNA
Sandra Blanchet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
A rationale for tRNA modification circuits in the anticodon loop
Lu Han et al.
RNA (2018)
The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential
Westley J. Friesen et al.
PLOS ONE (2018)
Optimized approach for the identification of highly efficient correctors of nonsense mutations in human diseases
Hana Benhabiles et al.
PLOS ONE (2017)
Aminoglycoside interactions and impacts on the eukaryotic ribosome
Irina Prokhorova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The nucleoside analog clitocine is a potent and efficacious readthrough agent
Westley J. Friesen et al.
RNA (2017)
Introduction of 2,6-Diaminopurines into Serinol Nucleic Acid Improves Anti-miRNA Performance
Yukiko Kamiya et al.
CHEMBIOCHEM (2017)
Nonsense-mediated mRNA decay at the crossroads of many cellular pathways
Fabrice Lejeune
BMB REPORTS (2017)
Gene-targeting pharmaceuticals for single-gene disorders
Arthur L. Beaudet et al.
HUMAN MOLECULAR GENETICS (2016)
Functional rescue of REP1 following treatment with PTC124 and novel derivative PTC-414 in human choroideremia fibroblasts and the nonsense-mediated zebrafish model
Mariya Moosajee et al.
HUMAN MOLECULAR GENETICS (2016)
Illumina-based RiboMethSeq approach for mapping of 2'-O-Me residues in RNA
Virginie Marchand et al.
NUCLEIC ACIDS RESEARCH (2016)
An integrated, structure- and energy-based view of the genetic code
Henri Grosjean et al.
NUCLEIC ACIDS RESEARCH (2016)
Mechanism and regulation of the nonsense-mediated decay pathway
Nele Hug et al.
NUCLEIC ACIDS RESEARCH (2016)
Antiviral activities of 2,6-diaminopurine-based acyclic nucleoside phosphonates against herpesviruses: In vitro study results with pseudorabies virus (PrV, SuHV-1)
Darina Zouharova et al.
VETERINARY MICROBIOLOGY (2016)
Genome recoding by tRNA modifications
Francesca Tuorto et al.
OPEN BIOLOGY (2016)
Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact
Evangelos D. Karousis et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2016)
Defects in tRNA Anticodon Loop 2′-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1
Michael P. Guy et al.
HUMAN MUTATION (2015)
European Medicines Agency review of ataluren for the treatment of ambulant patients aged 5 years and older with Duchenne muscular dystrophy resulting from a nonsense mutation in the dystrophin gene
Manuel Haas et al.
NEUROMUSCULAR DISORDERS (2015)
Synthetic Aminoglycosides Efficiently Suppress Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations and Are Enhanced by Ivacaftor
Xiaojiao Xue et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Therapeutics Based on Stop Codon Readthrough
Kim M. Keeling et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 15 (2014)
Designer Aminoglycosides That Selectively Inhibit Cytoplasmic Rather than Mitochondrial Ribosomes Show Decreased Ototoxicity A STRATEGY FOR THE TREATMENT OF GENETIC DISEASES
Eli Shulman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Dharma of Nonsense-Mediated mRNA Decay in Mammalian Cells
Maximilian Wei-Lin Popp et al.
MOLECULES AND CELLS (2014)
Modify or die? - RNA modification defects in metazoans
L. Peter Sarin et al.
RNA BIOLOGY (2014)
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial
Elton Kerem et al.
LANCET RESPIRATORY MEDICINE (2014)
The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome
Rebecca M. Voorhees et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Repair of UV photolesions in xeroderma pigmentosum group C cells induced by translational readthrough of premature termination codons
Christiane Kuschal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Read-through compound 13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy
Refik Kayali et al.
HUMAN MOLECULAR GENETICS (2012)
The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse
Dan Wang et al.
MOLECULAR GENETICS AND METABOLISM (2012)
Rescue of nonsense mutations by amlexanox in human cells
Sara Gonzalez-Hilarion et al.
ORPHANET JOURNAL OF RARE DISEASES (2012)
Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop
Michael P. Guy et al.
RNA (2012)
Sense from nonsense: therapies for premature stop codon diseases
Laure Bidou et al.
TRENDS IN MOLECULAR MEDICINE (2012)
Statistical Analysis of Readthrough Levels for Nonsense Mutations in Mammalian Cells Reveals a Major Determinant of Response to Gentamicin
Celia Floquet et al.
PLOS GENETICS (2012)
Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54
Steven M. Rowe et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
How mutations in tRNA distant from the anticodon affect the fidelity of decoding
T. Martin Schmeing et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Nonaminoglycoside compounds induce readthrough of nonsense mutations
Liutao Du et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Anti-proliferative effect of clitocine from the mushroom Leucopaxillus giganteus on human cervical cancer HeLa cells by inducing apoptosis
Gang Ren et al.
CANCER LETTERS (2008)
A meta-analysis of nonsense mutations causing human genetic disease
Matthew Mort et al.
HUMAN MUTATION (2008)
Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial
Eitan Kerem et al.
LANCET (2008)
The conserved Wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity
Monique Dewez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The use of β-D-2,6-diaminopurine dioxolane with or without mycophenolate mofetil in drug-resistant HIV infection
David M. Margolis et al.
AIDS (2007)
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
Jeffrey A. Engelman et al.
SCIENCE (2007)
PTC124 targets genetic disorders caused by nonsense mutations
Ellen M. Welch et al.
NATURE (2007)
Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin
Liat Linde et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges
Holly A. Kuzmiak et al.
TRENDS IN MOLECULAR MEDICINE (2006)
DHCR7 nonsense mutations and characterisation of mRNA nonsense mediated decay in Smith-Lemli-Opitz syndrome
LS Correa-Cerro et al.
JOURNAL OF MEDICAL GENETICS (2005)
Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment
L Bidou et al.
GENE THERAPY (2004)
Trm7p catalyses the formation of two 2′-O-methylriboses in yeast tRNA anticodon loop
L Pintard et al.
EMBO JOURNAL (2002)
Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system
M Manuvakhova et al.
RNA (2000)
Share Paper
