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Axonal excitability properties in amyotrophic lateral sclerosis
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M Manczak et al.
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S Qin et al.
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M Damiano et al.
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HR Ranaivo et al.
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L Berliocchi et al.
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J Koenigsknecht-Talboo et al.
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YE Kushnareva et al.
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GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis
P Van Damme et al.
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IG Stavrovskaya et al.
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K Erreger et al.
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T Eid et al.
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JD Rothstein et al.
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G Hoogland et al.
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DG Nicholls
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V Bancila et al.
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S Vesce et al.
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C Bendotti et al.
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H Guo et al.
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M Gottlieb et al.
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Proteomic identification of nitrated proteins in Alzheimer's disease brain
A Castegna et al.
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L Raiteri et al.
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M Amiry-Moghaddam et al.
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B Liu et al.
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NJ Haughey et al.
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M Aarts et al.
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M Mattiazzi et al.
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GE Hardingham et al.
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DM Walsh et al.
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JG Howland et al.
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EA Proper et al.
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PB Crino et al.
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R D'Ambrosio et al.
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SW Barger et al.
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DA Butterfield et al.
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S Cull-Candy et al.
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H Sato et al.
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MB O'Byrne et al.
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P Pasinelli et al.
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T González-Hernández et al.
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S Sasaki et al.
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E Aronica et al.
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LG Sheffield et al.
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CB Ransom et al.
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SX Hu et al.
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