Journal
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 11
Volume 11, Issue -, Pages 63-85Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-chembioeng-101519-121127
Keywords
bioprivileged molecules; biomass conversion; biological catalysis; chemical catalysis; platform technology
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Funding
- Center of Biorenewable Chemicals (CBiRC) - National Science Foundation [EEC-0813570]
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Further development of biomass conversions to viable chemicals and fuels will require improved atom utilization, process efficiency, and synergistic allocation of carbon feedstock into diverse products, as is the case in the well-developed petroleum industry. The integration of biological and chemical processes, which harnesses the strength of each type of process, can lead to advantaged processes over processes limited to one or the other. This synergy can be achieved through bioprivileged molecules that can be leveraged to produce a diversity of products, including both replacement molecules and novel molecules with enhanced performance properties. However, important challenges arise in the development of bioprivileged molecules. This review discusses the integration of biological and chemical processes and its use in the development of bioprivileged molecules, with a further focus on key hurdles that must be overcome for successful implementation.
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