Journal
VIRUSES-BASEL
Volume 12, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/v12030327
Keywords
circoviruses; redondoviruses; metagenomics; respiratory disease
Categories
Funding
- Instituto de Investigacion Carlos III [DTS 1500171]
- European Development Regional Fund A way to achieve Europe
- European Union Commission Future and Emerging Technologies Proactive 2016, under the Horizon 2020 Framework Programme [VIRUSCAN FETPROACT-2016-731868]
- Marie Sklodowska-Curie Individual Fellowships program (H2020-MSCA-IF-2017) [796084]
- Comunidad de Madrid, Consejeria de Educacion, Juventud y Deporte
- European Social Fund
- Youth Employment Initiative
- Marie Curie Actions (MSCA) [796084] Funding Source: Marie Curie Actions (MSCA)
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We used metagenomics to analyze one sputum sample from a patient with symptoms of a respiratory infection that yielded negative results for all pathogens tested. We detected two viral genomes that could be assembled and showed sequence similarity to redondoviruses, a recently described group within the CRESS-DNA viruses. One hundred sputum samples were screened for the presence of these viruses using specific primers. One sample was positive for the same two viruses, and another was positive for one of them. These findings raise questions about a possible role of redondoviruses in respiratory infections in humans.
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