Journal
ZYGOTE
Volume 28, Issue 4, Pages 270-277Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0967199420000222
Keywords
Cytokines; Domestic mammals; Follicular development; Protein expression; Receptors
Ask authors/readers for more resources
Tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) are cytokines that are involved in the development, proliferation and apoptosis of ovarian follicular cells in domestic mammals. The expression of these cytokines in various follicular compartments, depending on the stage of follicle development, demonstrates their involvement in the control of primordial follicle growth up to the preovulatory stage. The mechanism of action of these factors depends on the presence of their receptors that transduce their biological actions. This review shows the expression sites of TNF-alpha, IL-1 beta and their receptors in ovarian follicles, and discusses the mechanism of action of these cytokines during follicle development, oocyte maturation and ovulation in domestic animals.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available