Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 22, Issue 40, Pages 14166-14170Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201603496
Keywords
acedan; biosensors; fluorescence; hydrogen peroxide; visible color
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Funding
- Creative Research Initiative Grant - National Research Foundation of Korea (NRF) [2014R1A3A2030423]
- Bio & Medical Technology Development Program - National Research Foundation of Korea (NRF) [2012M3A9C4048780]
- National Research Foundation of Korea [2014R1A3A2030423, 2012M3A9C4048780] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Herein we report 22 acedan-derived, two-photon fluorophores with synthetic feasibility and full coverage of visible wavelength emission. The emission wavelengths were predicted by computational analysis, which enabled us to visualize multicolor images by two-photon excitation with single wavelength, and to design a turnon, two-photon fluorescence sensor for endogenous H2O2 in Raw 264.7 macrophage and rat brain hippocampus ex vivo.
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