Journal
TEXTILE RESEARCH JOURNAL
Volume 91, Issue 13-14, Pages 1478-1485Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0040517520925514
Keywords
antimicrobial nanofibrous membrane; curcumin; electrospinning; SEM; FTIR; Kirby Bauer disk diffusion test
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Curcumin, a naturally occurring compound, has various biological activities and can be incorporated into nanofibrous membranes for antimicrobial applications in the medical field.
Curcumin is a naturally occurring hydrophobic polyphenol compound. It exhibits a wide range of biological activities such as antibacterial, anti-inflammatory, anti-carcinogenic, antifungal, anti-HIV, and antimicrobial activity. In this research work, antimicrobial curcumin nanofibrous membranes are produce by an electrospinning technique using the Eudragit RS 100 (C19H34ClNO6) polymer solution enriched with curcumin. The morphology and chemistry of the membrane are analyzed using scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. Kirby Bauer disk diffusion tests are carried out to examine the antibacterial effectiveness of the membrane. Experimental results show that the nanofibers produced are of uniform thickness morphology and curcumin is successfully incorporated into the nanofibrous mat, while no chemical bonding was observed between curcumin and the polymer. The antimicrobial curcumin nanofibrous membranes can be effectively applied as antimicrobial barrier in a wide variety of medical applications such as wound healing, scaffolds, and tissue engineering.
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