4.5 Review

Recent Advances in Photocatalytic Decarboxylative Coupling Reactions in Medicinal Chemistry

Journal

SYNTHESIS-STUTTGART
Volume 52, Issue 12, Pages 1719-1737

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0039-1690843

Keywords

decarboxylation; photocatalysis; photoredox; medicinal chemistry; late-stage functionalisation; drug discovery

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This review covers recent advances in decarboxylative photocatalysis applicable to the medicinal chemist. The review is not intended to be exhaustive, but instead is focussed on transformations that could be useful in the synthesis of drug-like compounds in order to highlight the utility of this methodology in the development of new pharmaceutical candidates.

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