A novel, green environment-friendly cloud point extraction of polyphenols from pomegranate peels: a comparative assessment with ultrasound and microwave-assisted extraction

Pomegranate peel is a potential source of polyphenols, antioxidants, pectin, organic acids. Cloud point extraction (CPE) process parameters were optimized for efficient separation of polyphenols. Maximum extraction was obtained at 1:70 solid: solvent ratio, 8% (v/v) Triton X-114 at 55 degrees C, pH 4.5 with 14% NaCl for 30 minutes. Ultrasound assisted CPE showed maximum yield of total phenolic content (TPC; 96.28 mg GAE/g) and total flavonoids content (TFC; 12.27 mg QE/g) with 94.48% antioxidant activity (AA) to that of conventional, ultrasound and microwave-assisted CPE. These extractives can be labeled as green and may be used in food or dietary applications.

Automated summary

Pomegranate peel contains polyphenols, antioxidants, pectin, and organic acids. The cloud point extraction process parameters were optimized for efficient separation of polyphenols, achieving maximum extraction yield with ultrasound assistance. These extractives show high antioxidant activity and can be used in food or dietary applications as green alternatives.